Aspirin use to prevent preeclampsia and related morbidity and mortality: updated evidence report and systematic review for the US Preventive Services Task Force

JT Henderson, KK Vesco, CA Senger, RG Thomas… - Jama, 2021 - jamanetwork.com
Importance Preeclampsia is a hypertensive disorder of pregnancy that poses serious
maternal and infant health risks. Previous systematic reviews have established benefits of …

Preeclampsia: pathophysiology, challenges, and perspectives

S Rana, E Lemoine, JP Granger… - Circulation …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Aspirin use to prevent preeclampsia and related morbidity and mortality: US Preventive Services Task Force recommendation statement

KW Davidson, MJ Barry, CM Mangione, M Cabana… - Jama, 2021 - jamanetwork.com
Importance Preeclampsia is one of the most serious health problems that affect pregnant
persons. It is a complication in approximately 4% of pregnancies in the US and contributes …

Subtypes of preeclampsia: recognition and determining clinical usefulness

JM Roberts, JW Rich-Edwards, TF McElrath… - …, 2021 - Am Heart Assoc
The concept that preeclampsia is a multisystemic syndrome is appreciated in both research
and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …

[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders

S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled …

MK Hoffman, SS Goudar, BS Kodkany, M Metgud… - The Lancet, 2020 - thelancet.com
Background Preterm birth remains a common cause of neonatal mortality, with a
disproportionately high burden in low-income and middle-income countries. Meta-analyses …

Aspirin for the prevention of preterm and term preeclampsia: systematic review and metaanalysis

S Roberge, E Bujold, KH Nicolaides - American journal of obstetrics and …, 2018 - Elsevier
Objective Data Metaanalyses of randomized controlled trials have reported contradictory
results about the effect of aspirin in the prevention of preeclampsia, both in terms of the …

The role of aspirin dose on the prevention of preeclampsia and fetal growth restriction: systematic review and meta-analysis

S Roberge, K Nicolaides, S Demers, J Hyett… - American journal of …, 2017 - Elsevier
Background Preeclampsia and fetal growth restriction are major causes of perinatal death
and handicap in survivors. Randomized clinical trials have reported that the risk of …

Preeclampsia: maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors

T Tomimatsu, K Mimura, S Matsuzaki, M Endo… - International journal of …, 2019 - mdpi.com
Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …

Preeclampsia: pathogenesis, prevention, and long-term complications

B Jim, SA Karumanchi - Seminars in nephrology, 2017 - Elsevier
Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …