In the arena of functional group‐oriented organic synthesis, nitrile or cyano functionality is of
immense importance. The presence of nucleophilic N‐atom, π‐coordinating ability of the …

Oxidative reactions provide an effective strategy for phenol transformation via conjugated
addition, C–H functionalization, cyclization reactions, etc. It has enabled broad utilization of …

The synthesis of N-naphthyl pyrazoles has been realized by the direct three-component
reactions of enaminones, aryl hydrazine hydrochlorides and internal alkynes via Rh (III) …

By using readily available enaminones, aryl hydrazine hydrochlorides, and alkynes as
starting materials, the chemo-selective three-component synthesis of atropisomeric N-(o …

Twofold distal C− H functionalization was accomplished by difunctionalization of
nonactivated alkenes to provide rapid access to multifunctionalized molecules. The …

Alkynes are attractive synthons for organic chemistry. Despite the prevalence of transition-
metal-catalyzed Sonogashira reactions, a transition-metal-free version of the arylation of …

Regioselective C–H alkynylation of arenes via C–H activation is challenging yet a highly
desirable transformation. In this regard, directing group assisted C (sp2)–H alkynylation of …

We have come across a substrate namely, 5-benzoyl-pyrrolo [2, 1-a] isoquinoline in which
three different functionalizable C–H bonds were identified that could be judiciously …

In the realm of metallaphotocatalytic C− H activation strategy, the direct excitation of the
transition metal which plays the dual role of light energy harnessing alongside performing …

The isocyanate group in aryl isocyanates serves as a transformable transient directing group
in a Ru (II)-catalyzed ortho olefination leading to o-alkenylanilines. In alcoholic solvents, aryl …