The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …

NMR spectroscopy is a powerful tool for studying the structure, function and dynamics of
biological macromolecules. However, non‐spectroscopists often find NMR theory daunting …

Bacterial toxins damage the host at the site of bacterial infection or distant from the site.
Bacterial toxins can be single proteins or oligomeric protein complexes that are organized …

Viral capsid proteins assemble into large, symmetrical architectures that are not found in
complexes formed by their cellular counterparts. Given the prevalence of the signature jelly …

Yersiniosis is an infectious disease caused by Yersinia, food‐borne yersiniosis being due to
Yersinia enterocolitica or Yersinia pseudotuberculosis. Jerret and coworkers reported that Y …

Bacterial T cell superantigens (SAgs) are a family of microbial exotoxins that function to
activate large numbers of T cells simultaneously. SAgs activate T cells by direct binding and …

There are many different techniques available to biologists and biochemists that can be
used to detect and characterize the self-association of proteins. Each technique has …

This review is focused on methods for detecting small molecules and, in particular, the
characterisation of their interaction with natural proteins (eg receptors, ion channels) …

The lethal disease anthrax is propagated by spores of Bacillus anthracis, which can
penetrate into the mammalian host by inhalation, causing a rapid progression of the disease …

Leptospirosis, a spirochaetal zoonotic disease caused by Leptospira, has been recognized
as an important emerging infectious disease. LipL32 is the major exposed outer membrane …