The role of long non-coding RNAs in rheumatic diseases

Y Tang, T Zhou, X Yu, Z Xue, N Shen - Nature Reviews Rheumatology, 2017 - nature.com
Long non-coding RNAs (lncRNAs) have emerged as key epigenetic regulators that govern
gene expression and influence multiple biological processes. Accumulating evidence …

MicroRNAs and long non-coding RNAs in genetic diseases

A Finotti, E Fabbri, I Lampronti, J Gasparello… - Molecular Diagnosis & …, 2019 - Springer
Since the discovery and classification of non-coding RNAs, their roles have gained great
attention. In this respect, microRNAs and long non-coding RNAs have been firmly …

LncRNA PVT1 links Myc to glycolytic metabolism upon CD4+ T cell activation and Sjögren's syndrome-like autoimmune response

J Fu, H Shi, B Wang, T Zhan, Y Shao, L Ye, S Wu… - Journal of …, 2020 - Elsevier
The hyperproliferation and hyperactivation of CD4+ T cells in salivary gland tissue is a
hallmark of Sjögren's syndrome (SS). However, the role of long noncoding RNAs (lncRNAs) …

Innate immunity in Sjögren's syndrome

J Kiripolsky, LG McCabe, JM Kramer - Clinical immunology, 2017 - Elsevier
Sjögren's syndrome (SS) is an autoimmune disease of exocrine tissue that primarily affects
women. Although patients typically experience xerostomia and xerophthalmia, numerous …

Differential plasma expression profiles of long non-coding RNAs reveal potential biomarkers for systemic lupus erythematosus

GC Wu, Y Hu, SY Guan, DQ Ye, HF Pan - Biomolecules, 2019 - mdpi.com
Identify long non-coding RNAs (lncRNAs) that might serve as biomarkers for systemic lupus
erythematosus (SLE) and explore the biological functions of the identified lncRNAs. In the …

Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses

ML Joachims, B Khatri, C Li, KL Tessneer, JA Ice… - RMD open, 2022 - rmdopen.bmj.com
Objective Sjögren's disease (SjD) is an autoimmune disease characterised by inflammatory
destruction of exocrine glands. Patients with autoantibodies to Ro/SSA (SjDRo+) exhibit …

Long non-coding RNA expression profile in minor salivary gland of primary Sjögren's syndrome

H Shi, N Cao, Y Pu, L Xie, L Zheng, C Yu - Arthritis research & therapy, 2016 - Springer
Background To examine the roles of long noncoding RNAs (lncRNAs) in the regulation of
primary Sjögren's syndrome (pSS) and reveal the expression profile of lncRNAs in labial …

Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren's syndrome

J Inamo, K Suzuki, M Takeshita, Y Kassai… - Arthritis Research & …, 2020 - Springer
Background The aim of this study was to identify the molecular mechanism of dysregulation
of B cell subpopulations of primary Sjögren's syndrome (pSS) at the transcriptome level …

LncRNA and mRNA expression profile of peripheral blood mononuclear cells in primary Sjögren's syndrome patients

Y Peng, X Luo, Y Chen, L Peng, C Deng, Y Fei… - Scientific Reports, 2020 - nature.com
The aim of this study was to elucidate the expression profile and the potential role of long
non-coding RNA (LncRNA) in the peripheral blood mononuclear cells of primary Sjögren's …

The role of long non-coding RNAs in the pathogenesis of RA, SLE, and SS

Y Gao, S Li, Z Zhang, X Yu, J Zheng - Frontiers in medicine, 2018 - frontiersin.org
Rheumatoid diseases are a group of systemic autoimmune diseases which affect multiple
organs with largely unknown etiology. In the past decade, long non-coding RNAs (lncRNAs) …