Thalassemias are a group of inherited blood disorders that affects 5–7% of the world
population. Comprehensive screening strategies are essential for the management and …

This systematic literature review assessed the global prevalence and birth prevalence of
clinically significant forms of alpha‐and beta‐thalassemia. Embase, MEDLINE, and the …

Background Patients with transfusion-dependent thalassemia (TDT) require lifelong blood
transfusions and iron chelation therapy. Thus, patients afflicted with TDT often have to …

Background β-thalassaemia major poses a substantial economic burden, especially in
adults. We aimed to estimate the economic burden of adult patients with β-thalassaemia …

Thalassaemia constitutes an especially prevalent human monogenic illness caused by a
lack of synthesis of the α-or β-globin chains. The clinical impact of β-thalassaemia is worse …

Thalassemia is one of the most prevalent monogenic disorders in low-and middle-income
countries (LMICs). There are an estimated 270 million carriers of hemoglobinopathies …

Objectives Iron overload is a common complication experienced by transfusion-dependent
children with hemoglobin disorders. Chelators such as deferasirox (DFX) and deferiprone …

Vietnam has a high thalassemia burden. We collected blood samples from 5880 pregnant
Vietnamese women during prenatal health checks to assess thalassemia carrier frequency …

In 2016, a national school-based thalassemia screening programme was implemented in
Malaysia. This study aimed to explore the experiences and views of adolescents from an …

Background: Cardiac complications in patients with transfusion-dependent thalassemia
(TDT) are one of the ma-jor causes of mortality in these patients which annually impose …