Neural stem cells in the adult mammalian brain are the source of new neurons that
contribute to complex sensory and cognitive functions. Most adult neural stem cells are …

Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

Extracellular vesicles (EVs) released by neural cells play an essential role in brain
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …

Hippocampal neurogenesis continues throughout life and has been suggested to play an
essential role in maintaining spatial cognitive function under physiological conditions. An …

Aging causes changes in the hippocampus that may lead to cognitive decline in older
adults. In young animals, exercise increases hippocampal neurogenesis and improves …

The current study examined how a randomized one-year aerobic exercise program for
healthy older adults would affect serum levels of brain-derived neurotrophic factor (BDNF) …

Emerging data indicate that progesterone has multiple non-reproductive functions in the
central nervous system to regulate cognition, mood, inflammation, mitochondrial function …

A growing body of literature suggests that physical activity beneficially influences brain
function during adulthood, particularly frontal lobe-mediated cognitive processes, such as …