Current status and future prospective of vaccine development against Echinococcus granulosus

MM Pourseif, G Moghaddam, N Saeedi, A Barzegari… - Biologicals, 2018 - Elsevier
Cystic echinococcosis (CE) is one of the most important zoonotic parasite diseases in
human, livestock, and wildlife worldwide. Development of effective vaccines against CE …

Computational immunology: The coming of age

N Petrovsky, V Brusic - Immunology and cell biology, 2002 - Wiley Online Library
The explosive growth in biotechnology combined with major advances in information
technology has the potential to radically transform immunology in the postgenomics era. Not …

Silent mutations affect in vivo protein folding in Escherichia coli

P Cortazzo, C Cerveñansky, M Marı́n, C Reiss… - Biochemical and …, 2002 - Elsevier
As an approach to investigate the molecular mechanism of in vivo protein folding and the
role of translation kinetics on specific folding pathways, we made codon substitutions in the …

The crystal structure of Echinococcus granulosus fatty-acid-binding protein 1

E Jakobsson, G Alvite, T Bergfors, A Esteves… - … et Biophysica Acta (BBA …, 2003 - Elsevier
We describe the 1.6 Å crystal structure of the fatty-acid-binding protein EgFABP1 from the
parasitic platyhelminth Echinococcus granulosus. E. granulosus causes hydatid disease …

Binding properties of Echinococcus granulosus fatty acid binding protein

G Alvite, SM Di Pietro, JA Santomé, R Ehrlich… - … et Biophysica Acta (BBA …, 2001 - Elsevier
EgFABP1 is a developmentally regulated intracellular fatty acid binding protein
characterized in the larval stage of parasitic platyhelminth Echinococcus granulosus. It is …

Genomic structure and expression of a gene coding for a new fatty acid binding protein from Echinococcus granulosus

A Esteves, V Portillo, R Ehrlich - … et Biophysica Acta (BBA)-Molecular and …, 2003 - Elsevier
This work describes a new gene coding for a fatty acid binding protein (FABP) in the parasite
Echinococcus granulosus, named EgFABP2. The complete gene structure, including the …

Linking murine resistance to secondary cystic echinococcosis with antibody responses targeting Echinococcus granulosus tegumental antigens

S Miles, J Magnone, M Cyrklaff, P Arbildi… - Immunobiology, 2020 - Elsevier
Successful establishment of a parasite infection depends partially on the host intrinsic
susceptibility to the pathogen. In cystic echinococcosis (CE), a zoonotic disease caused by …

Human Secretory Immune Response to Fatty Acid-Binding Protein Fraction from Giardia lamblia

SMT Hasan, M Maachee, OM Córdova… - Infection and …, 2002 - Am Soc Microbiol
The secretory immune response in humans infected with Giardia lamblia was studied by
using saliva samples and an 8-kDa antigen capable of binding fatty acids. This antigen was …

Echinococcus granulosus fatty acid binding proteins subcellular localization

G Alvite, A Esteves - Experimental parasitology, 2016 - Elsevier
Two fatty acid binding proteins, EgFABP1 and EgFABP2, were isolated from the parasitic
platyhelminth Echinococcus granulosus. These proteins bind fatty acids and have particular …

Modelling and study of cyclosporin A and related compounds in complexes with a Trypanosoma cruzi cyclophilin

R Carraro, J Búa, A Ruiz, M Paulino - Journal of Molecular Graphics and …, 2007 - Elsevier
Cyclophilins (CyPs) are enzymes involved in protein folding, catalyzing the isomerisation of
peptidyl prolyl bonds in proteins and peptides between the cis-and trans-conformations …