Immune system and COVID-19 by sex differences and age

T Ciarambino, O Para, M Giordano - Women's Health, 2021 - journals.sagepub.com
In COVID-19 disease, are reported gender differences in relation to severity and death. The
aim of this review is to highlight gender differences in the immune response to COVID-19 …

Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

Systematic review and meta-analysis of sex-specific COVID-19 clinical outcomes

T Galbadage, BM Peterson, J Awada, AS Buck… - Frontiers in …, 2020 - frontiersin.org
To successfully mitigate the extraordinary devastation caused by the Coronavirus disease
2019 (COVID-19) pandemic, it is crucial to identify important risk factors for this disease. One …

Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2

S Sun, H Gu, L Cao, Q Chen, Q Ye, G Yang… - Nature …, 2021 - nature.com
There is an urgent need for animal models to study SARS-CoV-2 pathogenicity. Here, we
generate and characterize a novel mouse-adapted SARS-CoV-2 strain, MASCp36, that …

Sex‐related differences in COVID‐19 lethality

C Penna, V Mercurio, CG Tocchetti… - British journal of …, 2020 - Wiley Online Library
Many countries have been affected by the worldwide outbreak of COVID‐19. Among
Western countries, Italy has been particularly hit at the beginning of the pandemic …

Risk factors, presentation, and course of coronavirus disease 2019 in a large, academic long-term care facility

SM Shi, I Bakaev, H Chen, TG Travison… - Journal of the American …, 2020 - Elsevier
Objective To describe clinical characteristics and risk factors associated with coronavirus
disease 2019 (COVID-19) in long-stay nursing home residents. Design and Participants …

Genetic and epigenetic factors associated with increased severity of Covid‐19

Z Yildirim, OS Sahin, S Yazar… - Cell biology …, 2021 - Wiley Online Library
Since December 2019, a new form of severe acute respiratory syndrome (SARS) from a
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …

Men and COVID-19: the aftermath

A White - Postgraduate Medicine, 2020 - Taylor & Francis
The global pandemic as a result of the SARS-CoV2 virus has seen over 16 m people
infected and over 650,000 deaths, with men at double the risk of both developing the severe …

Immunosenescence and inflamm-ageing in COVID-19

MR Zinatizadeh, PK Zarandi, M Ghiasi… - Ageing Research …, 2023 - Elsevier
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

Sex hormones, autoimmunity and gender disparity in COVID-19

HA Raza, P Sen, OA Bhatti, L Gupta - Rheumatology international, 2021 - Springer
Abstract The Coronavirus disease 2019 (COVID-19) pandemic has majorly contributed to
massive and widespread mortality. Epidemiological data strongly indicates a sex-based …