In recent years, oncolytic virotherapy has emerged as a promising anticancer therapy.
Oncolytic viruses destroy cancer cells, without damaging normal tissues, through virus self …

Chimeric antigen receptor (CAR) T-cell therapy is a promising and rapidly expanding
therapeutic option for a wide range of human malignancies. Despite the ongoing progress of …

Basic and clinical studies have demonstrated the efficacy of immunotherapy, a technical and
conceptual breakthrough that has revolutionised cancer treatment. Hepatocellular …

Within the last decade, the introduction of checkpoint inhibitors proposed to boost the
patients' anti-tumor immune response has proven the efficacy of immunotherapeutic …

Hepatocellular Carcinoma (HCC) is a highly prevalent malignancy that develops in patients
with chronic liver diseases and dysregulated systemic and hepatic immunity. The tumor …

According to the World Health Organization, cancer is one of the leading global health
concerns, causing nearly 10 million deaths in 2020. While classical chemotherapeutics …

Using viruses to our advantage has been a huge leap for humanity. Their ability to mediate
horizontal gene transfer has made them useful tools for gene therapy, vaccine development …

Simple Summary Even though it is known that (cancer) cells can fuse, it is still less
understood how (cancer) cells merge their plasma membranes, thereby giving rise to bi-and …

RNA viruses have been subjected to substantial engineering efforts to support gene therapy
applications and vaccine development. Typically, retroviruses, lentiviruses, alphaviruses …

Oncolytic virotherapy (OVT) is a novel form of immunotherapy using natural or genetically
modified viruses to selectively replicate in and kill malignant cells. Many genetically modified …