Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Carbapenem-resistant Enterobacteriaceae (CRE) are a serious public health threat.
Infections due to these organisms are associated with significant morbidity and mortality …

The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-
health problem of global dimensions. This type of antimicrobial resistance, especially when …

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …

Multilocus sequence typing reveals that many bacterial species have a clonal structure and
that some clones are widespread. This underlying phylogeny was not revealed by pulsed …

Health care-associated infections (HAIs) have become more common as medical care has
grown more complex and patients have become more complicated. HAIs are associated …

From early this decade, Enterobacteriaceae that produce Klebsiella pneumoniae
carbapenemases (KPC) were reported in the USA and subsequently worldwide. These KPC …

Bacteria producing Klebsiella pneumoniae carbapenemases (KPCs) are rapidly emerging
as a cause of multidrug-resistant infections worldwide. Bacterial isolates harbouring these …