[HTML][HTML] Soft drusen in age-related macular degeneration: biology and targeting via the oil spill strategies

CA Curcio - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

[HTML][HTML] Neovascular age-related macular degeneration: therapeutic management and new-upcoming approaches

F Ricci, F Bandello, P Navarra, G Staurenghi… - International journal of …, 2020 - mdpi.com
Age-related macular degeneration (AMD) constitutes a prevalent, chronic, and progressive
retinal degenerative disease of the macula that affects elderly people and cause central …

Towards a better understanding of non-exudative choroidal and macular neovascularization

R Sacconi, S Fragiotta, D Sarraf, SVR Sadda… - Progress in Retinal and …, 2023 - Elsevier
Non-exudative macular and choroidal neovascularization (MNV and CNV) usually refers to
the entity of treatment-naïve type 1 neovascularization in the absence of associated signs of …

Subretinal drusenoid deposits AKA pseudodrusen

RF Spaide, S Ooto, CA Curcio - Survey of ophthalmology, 2018 - Elsevier
A distinction between conventional drusen and pseudodrusen was first made in 1990, and
more recently knowledge of pseudodrusen, more accurately called subretinal drusenoid …

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related …

GS Hageman, PJ Luthert, NHV Chong… - Progress in retinal and …, 2001 - Elsevier
Age-related macular degeneration (AMD) is a blinding disease that afflicts millions of adults
in the Western world. Although it has been proposed that a threshold event occurs during …

Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies

J Ambati, BK Ambati, SH Yoo, S Ianchulev… - Survey of …, 2003 - Elsevier
Age-related macular degeneration is the principal cause of registered legal blindness
among those aged over 65 in the United States, western Europe, Australia, and Japan …

Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography

T Desmettre, JM Devoisselle, S Mordon - Survey of ophthalmology, 2000 - Elsevier
Indocyanine green (ICG) is a fluorescent dye that has been used for the imaging of retinal
and choroidal vasculatures for more than 30 years. Its high molecular weight, specific …

Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts

KM Gehrs, DH Anderson, LV Johnson… - Annals of …, 2006 - Taylor & Francis
Today, the average life expectancy in developed nations is over 80 years and climbing. And
yet, the quality of life during those additional years is often significantly diminished by the …

Current concepts in the pathogenesis of age-related macular degeneration

MA Zarbin - Archives of ophthalmology, 2004 - jamanetwork.com
Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …

Lutein, zeaxanthin, and the macular pigment

JT Landrum, RA Bone - Archives of biochemistry and biophysics, 2001 - Elsevier
The predominant carotenoids of the macular pigment are lutein, zeaxanthin, and meso-
zeaxanthin. The regular distribution pattern of these carotenoids within the human macula …