OBJECTIVE: To develop comprehensive clinical practice guidelines for critically ill infants
and children, with specific attention to seven domains of care including pain …

Abstract Purpose of the Review Review recent advances in pain, sedation, and delirium
management in the pediatric intensive care unit (PICU) and how they may benefit critically …

Objectives To conduct a scoping review of sedation clinical trials in the paediatric intensive
care setting and summarise key methodological elements. Design Scoping review. Data …

Background Analgesics and sedatives are key elements to reduce physiological and
psychological stress associated with treatment in paediatric intensive care. Prolonged drug …

Background Bronchoscopy can be a distress for the patient. There have been few studies on
the combination of sedatives and opioids. The aim of this study was to demonstrate the …

Aim Although not approved, the α‐adrenoceptor agonist clonidine is considered an option
for long‐term sedation protocols in paediatric intensive care. We reviewed adverse effects of …

SUMMARY OBJECTIVE: This study aimed to assess the clonidine infusion rate in the first 6
h, as maintenance dose (first 24 h), and in the pre-extubation period (last 24 h), as well as …

Aims Research involving analgo-sedation is a priority for parents and professionals in
paediatric intensive care, and current guidelines are based on low-quality evidence. Future …

S3-Leitlinie Analgesie, Sedierung und Delirmanagement in der Intensivmedizin (DAS-Leitlinie
2020) Page 1 1 S3-Leitlinie Analgesie, Sedierung und Delirmanagement in der Intensivmedizin …

Objective: Fentanyl and midazolam are popular drugs for sedation and analgesia in
intensive care unit. Gabapentin has sedative and analgesic effects, as well. Our purpose …