The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Engineered nanomedicines with enhanced tumor penetration

J Ding, J Chen, L Gao, Z Jiang, Y Zhang, M Li, Q Xiao… - Nano Today, 2019 - Elsevier
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy's history, efficacy and application in humans

K Mahmoudi, A Bouras, D Bozec, R Ivkov… - International Journal …, 2018 - Taylor & Francis
Hyperthermia therapy (HT) is the exposure of a region of the body to elevated temperatures
to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer …

Synergic effects of nanoparticles-mediated hyperthermia in radiotherapy/chemotherapy of cancer

K Mortezaee, A Narmani, M Salehi, H Bagheri… - Life sciences, 2021 - Elsevier
The conventional cancer treatment modalities such as radiotherapy and chemotherapy
suffer from several limitations; hence, their efficiency needs to be improved with other …

Biocompatible nanoclusters with high heating efficiency for systemically delivered magnetic hyperthermia

HA Albarqi, LH Wong, C Schumann, FY Sabei… - ACS …, 2019 - ACS Publications
Despite its promising therapeutic potential, nanoparticle-mediated magnetic hyperthermia is
currently limited to the treatment of localized and relatively accessible cancer tumors …

Emerging strategies in developing multifunctional nanomaterials for cancer nanotheranostics

MJY Ang, SY Chan, YY Goh, Z Luo, JW Lau… - Advanced Drug Delivery …, 2021 - Elsevier
Cancer involves a collection of diseases with a common trait–dysregulation in cell
proliferation. At present, traditional therapeutic strategies against cancer have limitations in …

Controlled drug delivery systems for oral cancer treatment—current status and future perspectives

F Ketabat, M Pundir, F Mohabatpour, L Lobanova… - Pharmaceutics, 2019 - mdpi.com
Oral squamous cell carcinoma (OSCC), which encompasses the oral cavity-derived
malignancies, is a devastating disease causing substantial morbidity and mortality in both …

An implantable smart hyperthermia nanofiber with switchable, controlled and sustained drug release: Possible application in prevention of cancer local recurrence

S Samadzadeh, M Babazadeh, N Zarghami… - Materials Science and …, 2021 - Elsevier
Temperature-responsive drug-loaded electrospun nanofibers have gained huge critical
attention as efficient localized implantable devices in preventing cancer local recurrence. In …

Target delivery of doxorubicin tethered with PVP stabilized gold nanoparticles for effective treatment of lung cancer

V Ramalingam, K Varunkumar, V Ravikumar… - Scientific reports, 2018 - nature.com
Abstract Development of drug delivery system conjugated with doxorubicin (dox) on the
surface of AuNPs with polyvinylpyrrolidone (Dox@ PVP-AuNPs), we have demonstrated that …

Advances in porous silicon–based nanomaterials for diagnostic and therapeutic applications

T Tieu, M Alba, R Elnathan… - Advanced …, 2019 - Wiley Online Library
This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …