Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms

FJ Vernerey, S Lalitha Sridhar, A Muralidharan… - Chemical …, 2021 - ACS Publications
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Engineering immunomodulatory biomaterials to tune the inflammatory response

A Vishwakarma, NS Bhise, MB Evangelista… - Trends in …, 2016 - cell.com
Current state-of-the-art biomedical implants and tissue engineering methods promise
technologies to improve or even restore the function of diseased organs. However, one of …

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011 - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

Hydrogels for protein delivery in tissue engineering

R Censi, P Di Martino, T Vermonden… - Journal of Controlled …, 2012 - Elsevier
Tissue defects caused by diseases or trauma present enormous challenges in regenerative
medicine. Recently, a better understanding of the biological processes underlying tissue …

PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids

CC Lin, A Raza, H Shih - Biomaterials, 2011 - Elsevier
Hydrogels provide three-dimensional frameworks with tissue-like elasticity and high
permeability for culturing therapeutically relevant cells or tissues. While recent research …

Peptide hydrogels as immunomaterials and their use in cancer immunotherapy delivery

N Falcone, M Ermis, DG Tamay… - Advanced …, 2023 - Wiley Online Library
Peptide‐based hydrogel biomaterials have emerged as an excellent strategy for immune
system modulation. Peptide‐based hydrogels are supramolecular materials that self …

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

KM Schultz, KA Kyburz… - Proceedings of the …, 2015 - National Acad Sciences
Biomaterials that mimic aspects of the extracellular matrix by presenting a 3D
microenvironment that cells can locally degrade and remodel are finding increased …

Biomaterials for personalized cell therapy

AL Facklam, LR Volpatti, DG Anderson - Advanced materials, 2020 - Wiley Online Library
Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

Affinity-based growth factor delivery using biodegradable, photocrosslinked heparin-alginate hydrogels

O Jeon, C Powell, LD Solorio, MD Krebs… - Journal of Controlled …, 2011 - Elsevier
Photocrosslinkable biomaterials are promising for tissue engineering applications due to
their capacity to be injected and form hydrogels in situ in a minimally invasive manner. Our …