A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug Discovery
The COVID-19 pandemic has intensively disrupted global health, economics, and well-
being. Andrographis paniculata (Burm. f.) Nees has been used as a complementary …
being. Andrographis paniculata (Burm. f.) Nees has been used as a complementary …
The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse
AC Kruegel, O Grundmann - Neuropharmacology, 2018 - Elsevier
The leaves of Mitragyna speciosa (commonly known as kratom), a tree endogenous to parts
of Southeast Asia, have been used traditionally for their stimulant, mood-elevating, and …
of Southeast Asia, have been used traditionally for their stimulant, mood-elevating, and …
From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction
Kratom (or Ketum) is a psychoactive plant preparation used in Southeast Asia. It is derived
from the plant Mitragyna speciosa Korth. Kratom as well as its main alkaloid, mitragynine …
from the plant Mitragyna speciosa Korth. Kratom as well as its main alkaloid, mitragynine …
Hepatoprotective Effects of Orthosiphon stamineus Extract on Thioacetamide‐Induced Liver Cirrhosis in Rats
Orthosiphon stamineus as medicinal plant is commonly used in Malaysia for treatment of
hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the …
hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the …
In Vitro Antidiabetic Activity and Mechanism of Action of Brachylaena elliptica (Thunb.) DC
IJ Sagbo, M van de Venter… - Evidence‐Based …, 2018 - Wiley Online Library
In South Africa, the number of people suffering from diabetes is believed to be rising steadily
and the current antidiabetic therapies are frequently reported to have adverse side effects …
and the current antidiabetic therapies are frequently reported to have adverse side effects …
Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay
The extract from Mitragyna speciosa has been widely used as an opium substitute, mainly
due to its morphine-like pharmacological effects. This study investigated the effects of M …
due to its morphine-like pharmacological effects. This study investigated the effects of M …
[HTML][HTML] Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities
NA Hanapi, S Ismail, SM Mansor - Pharmacognosy research, 2013 - ncbi.nlm.nih.gov
Aims: This study was conducted to determine the inhibitory effects of mitragynine on
cytochrome P450 2C9, 2D6 and 3A4 activities. Methods and Material: The in vitro study was …
cytochrome P450 2C9, 2D6 and 3A4 activities. Methods and Material: The in vitro study was …
[HTML][HTML] Effects of Curcuma xanthorrhiza extracts and their constituents on phase II drug-metabolizing enzymes activity
NAM Salleh, S Ismail, MR Ab Halim - Pharmacognosy Research, 2016 - ncbi.nlm.nih.gov
Background: Curcuma xanthorrhiza is a native Indonesian plant and traditionally utilized for
a range of illness including liver damage, hypertension, diabetes, and cancer. Objective …
a range of illness including liver damage, hypertension, diabetes, and cancer. Objective …
Kratom: A systematic review of toxicological issues
S Kerrigan, S Basiliere - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Kratom is a botanical substance derived from the leaves of Mitragyna speciosa. Although
kratom has been used traditionally in Southeast Asia for over a century, recreational use and …
kratom has been used traditionally in Southeast Asia for over a century, recreational use and …
A critical review of the neuropharmacological effects of kratom: An insight from the functional array of identified natural compounds
Kratom (Mitragyna speciosa Korth. Havil) has been considered a narcotic drug for years,
barred by the law in many parts of the world, while extensive research over the past few …
barred by the law in many parts of the world, while extensive research over the past few …