Anti-NMDA receptor autoimmune encephalitis: diagnosis and management strategies

L Nguyen, C Wang - International journal of general medicine, 2023 - Taylor & Francis
Abstract Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most recognized
form of autoimmune encephalitis. It is characterized by a constellation of neurologic and …

Immunotherapy for refractory autoimmune encephalitis

J Yang, X Liu - Frontiers in Immunology, 2021 - frontiersin.org
Autoimmune encephalitis (AE) is an immune-mediated disease involving the central
nervous system, usually caused by antigen-antibody reactions. With the advent of …

Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes

WJ Lee, HS Lee, DY Kim, HS Lee, J Moon, KI Park… - Brain, 2022 - academic.oup.com
Seronegative autoimmune encephalitis is autoimmune encephalitis without any identifiable
pathogenic antibody. Although it is a major subtype of autoimmune encephalitis, many …

Neuroinflammation in obsessive-compulsive disorder: Sydenham chorea, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections …

A Vreeland, M Thienemann, M Cunningham… - Psychiatric …, 2023 - psych.theclinics.com
Postinfectious neuroinflammation has been implicated in models of acute onset obsessive-
compulsive disorder (OCD) in children since the description of pediatric autoimmune …

Immunotherapy in autoimmune encephalitis

BP Trewin, I Freeman, S Ramanathan… - Current Opinion in …, 2022 - journals.lww.com
Early first-line immunotherapies, including corticosteroids and plasma exchange, improve
outcomes, with emerging evidence showing second-line immunotherapies (especially …

Current status and prospects of IL-6–targeting therapy

M Narazaki, T Kishimoto - Expert Review of Clinical Pharmacology, 2022 - Taylor & Francis
Introduction Persistent and excess IL-6 production often contributes to a variety of immune
diseases. IL-6–targeting therapy was first approved for Castleman disease, then rheumatoid …

Cytokine dynamics and targeted immunotherapies in autoimmune encephalitis

NL Ciano-Petersen, S Muñiz-Castrillo… - Brain …, 2022 - academic.oup.com
Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous
system disorders mainly characterized by the presence of antibodies targeting neuronal or …

Clinical features and therapeutic effects of anti-leucine-rich glioma inactivated 1 encephalitis: a systematic review

Y Teng, T Li, Z Yang, M Su, J Ni, M Wei, J Shi… - Frontiers in …, 2022 - frontiersin.org
Background: Clinical presentations and treatment programs about anti-leucine-rich glioma
inactivated 1 (LGI1) encephalitis still remain incompletely understood. Objective: This study …

Development and validation of a risk score to differentiate viral and autoimmune encephalitis in adults

A Granillo, M Le Maréchal, L Diaz-Arias… - Clinical Infectious …, 2023 - academic.oup.com
Background Encephalitis represents a challenging condition to diagnose and treat. To assist
physicians in considering autoimmune encephalitis (AE) sooner, we developed and …

Autoimmune encephalitis in children

D Hardy - Pediatric Neurology, 2022 - Elsevier
Autoimmune encephalitis is a group of central nervous system (CNS) inflammatory disorders
that most commonly affect young adults and children. These disorders are closely …