Amide activation: an emerging tool for chemoselective synthesis

D Kaiser, A Bauer, M Lemmerer… - Chemical Society Reviews, 2018 - pubs.rsc.org
It is textbook knowledge that carboxamides benefit from increased stabilisation of the
electrophilic carbonyl carbon when compared to other carbonyl and carboxyl derivatives …

Synthesis of Enantiopure trans-3,4-Disubstituted Piperidines. An Enantiodivergent Synthesis of (+)- and (−)-Paroxetine

M Amat, J Bosch, J Hidalgo, M Cantó… - The Journal of …, 2000 - ACS Publications
Reaction of (R)-phenylglycinol with methyl 5-oxopentanoate gave either bicyclic lactam cis-1
(the kinetic product) or its isomer trans-1 (under equilibrating conditions) as the major …

Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl) ethoxy]-2, 6-diarylpiperidin-4-ones

C Ramalingan, S Balasubramanian, S Kabilan… - European journal of …, 2004 - Elsevier
Some novel benzoxazolylethoxypiperidones have been synthesized and their antibacterial
activity against streptococcus faecalis, bacillus subtilis, escherichia coli, staphylococcus …

Enantioselective syntheses of 2-alkyl-and 2, 6-dialkylpiperidine alkaloids: preparations of the hydrochlorides of (−)-coniine,(−)-solenopsin A, and (−)-dihydropinidine

TJ Wilkinson, NW Stehle, P Beak - Organic Letters, 2000 - ACS Publications
Sequences of lithiation− substitution, enantioselective hydrogenation, and
diastereoselective lithiation− substitution provide efficient highly enantioselective syntheses …

Influence of organic structure directing agent isomer distribution on the synthesis of SSZ-39

M Dusselier, JE Schmidt, R Moulton… - Chemistry of …, 2015 - ACS Publications
The aluminosilicate molecular sieve with the AEI framework topology (SSZ-39) is currently of
great interest for use in a number of important applications such as exhaust gas NO x …

Synthesis of tricyclic marine alkaloids, cylindricines, lepadiformines, fasicularin, and polycitorols: a recent update

A Kaga, S Chiba - Synthesis, 2018 - thieme-connect.com
Cylindricines, lepadiformines, and fasicularin are tricyclic marine alkaloids bearing
perhydropyrrolo-and pyrido [2, 1-j] frameworks having divergent chemical functionalities …

Synthesis and in vitro microbiological evaluation of imidazo (4, 5-b) pyridinylethoxypiperidones

G Aridoss, S Balasubramanian, P Parthiban… - European journal of …, 2006 - Elsevier
A series of imidazo (4, 5-b) pyridinylethoxypiperidones was designed, synthesized and
characterized for evaluation of potential antibacterial activity against Bacillus subtilis …

Dynamic kinetic resolution of racemic γ-aryl-δ-oxoesters. Enantioselective synthesis of 3-arylpiperidines

M Amat, M Cantó, N Llor, C Escolano… - The Journal of …, 2002 - ACS Publications
Cyclodehydration of racemic γ-aryl-δ-oxoesters with (R)-or (S)-phenylglycinol
stereoselectively affords bicyclic δ-lactams, in a process that involves a dynamic kinetic …

Conjugate Addition of Organocuprates to Chiral Bicyclic δ-Lactams. Enantioselective Synthesis of cis-3,4-Disubstituted and 3,4,5-Trisubstituted Piperidines

M Amat, M Pérez, N Llor, J Bosch, E Lago… - Organic …, 2001 - ACS Publications
Chiral nonracemic bicyclic lactam 3, easily accessible by cyclodehydration of (R)-
phenylglycinol and racemic methyl 4-formylhexanoate, was converted to the unsaturated …

Asymmetric Synthesis of Ring Functionalized trans-2,6-Disubstituted Piperidines from N-Sulfinyl δ-Amino β-Keto Phosphonates. Total Synthesis of (−)-Myrtine

FA Davis, H Xu, J Zhang - The Journal of organic chemistry, 2007 - ACS Publications
Asymmetric Synthesis of Ring Functionalized trans-2,6-Disubstituted Piperidines from N-Sulfinyl
δ-Amino β-Keto Phosphonates. Total Synthesis of (−)-Myrtine | The Journal of Organic Chemistry …