Traditional vaccines use inactivated or weakened forms of pathogens which could have side
effects and inadequate immune responses. To overcome these challenges, phage display …

The SARS-CoV-2 nucleocapsid protein is indispensable for viral RNA genome processing.
Although the N-terminal domain (NTD) is suggested to mediate specific RNA-interactions …

Abstract The Poisson-Boltzmann (PB) model governs the electrostatics of solvated
biomolecules, ie, potential, field, energy, and force. These quantities can provide useful …

Future pandemic threats may be caused by novel coronaviruses and influenza A viruses.
Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its …

Coronavirus nucleocapsid protein (NP) of SARS-CoV-2 plays a central role in many
functions important for virus proliferation including packaging and protecting genomic RNA …

The nucleocapsid (N) protein is one of the four structural proteins in SARS-CoV-2, playing
key roles in viral assembly, immune evasion, and stability. One of its primary functions is to …

Traditional vaccines use inactivated or weakened forms of pathogens which could have side
effects and inadequate immune responses. To overcome these challenges, phage display …

The Poisson-Boltzmann (PB) model governs the electrostatics of solvated biomolecules, ie,
potential, field, energy, and force. These quantities can provide useful information about …

We investigate machine learning and electrostatic methods to predict biophysical properties
of proteins, such as solvation energy and protein ligand binding affinity, for the purpose of …

The SARS-CoV-2 nucleocapsid protein is indispensable for processing of the viral RNA
genome. The N-terminal domain (NTD) was suggested to mediate specific RNA-interactions …