A snake cathelicidin enhances transcription factor EB‐mediated autophagy and alleviates ROS‐induced pyroptosis after ischaemia–reperfusion injury of island skin …

N Yang, G Yu, Y Lai, J Zhao, Z Chen… - British Journal of …, 2024 - Wiley Online Library
Background and Purpose Ischaemia–reperfusion (I/R) injury is a major contributor to skin
flap necrosis, which presents a challenge in achieving satisfactory therapeutic outcomes …

Apilarnil exerts neuroprotective effects and alleviates motor dysfunction by rebalancing M1/M2 microglia polarization, regulating miR-155 and miR-124 expression in a …

RM Salama, SF Darwish, R Yehia, N Eissa… - International …, 2024 - Elsevier
Microglial activation contributes to the neuropathology of Parkinson's disease (PD).
Inhibiting M1 while simultaneously boosting M2 microglia activation may therefore be a …

Exploring the Chemical Constituents and Nutritive Potential of Bee Drone (Apilarnil): Emphasis on Antioxidant Properties

AA Abd El‐Wahed, SAM Khalifa… - Chemistry & …, 2024 - Wiley Online Library
A lesser‐known bee product called drone brood homogenate (DBH, apilarnil) has recently
attracted scientific interest for its chemical and biological properties. It contains …

[HTML][HTML] Inhibitions inflammatory response in clicks alleviates LPS induced myocardial injury by total polysaccharides of Pinus massoniana Lamb. pollen

C Wang, H Shang, S Zhang, X Wang, M Shen… - Carbohydrate Polymer …, 2023 - Elsevier
Total polysaccharides of Pinus massoniana Lamb. pollen (PPPS t) is a natural carbohydrate
with known anti-inflammatory effects. Inflammation was the main cause of death due to …

Protective role of olive oil extract of propolis on short and long‐term administration of tamoxifen in rats

S Silici, L Kaynar, A Okan… - Environmental …, 2024 - Wiley Online Library
Tamoxifen (TAM) is an antiestrogenic agent used for adjuvant treatment in estrogen receptor‐
positive breast cancers in the pre/post‐menopausal period. This study, it was aimed to …

Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF‐κB/TNF‐α signaling pathways: Experimental study

A Okan, Z Doğanyiğit, S Yilmaz, S Uçar… - Cell Biochemistry …, 2023 - Wiley Online Library
The development and progression of sepsis are multifactorial and influence the
immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the …

Drone Larvae Homogenate (Apilarnil) as Natural Remedy: Scientific Review

S Silici - Journal of Agricultural Sciences, 2023 - dergipark.org.tr
For centuries, honey bee products such as honey, bee pollen, royal jelly, bee bread (Perga),
and bee venom have been utilized in natural medicine due to their beneficial properties. A …

Calcium dobesilate alleviates renal dysfunction and inflammation by targeting nuclear factor kappa B (NF-κB) signaling in sepsis-associated acute kidney injury

Z Xie, L Wei, J Chen, Z Chen - Bioengineered, 2022 - Taylor & Francis
Acute kidney injury (AKI) is a serious complication of sepsis that increases mortality and the
risk of progression to chronic kidney disease. Oxidative stress and apoptosis are reported to …

Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region‐associated protein synthesis and TLR4/NF‐κB signaling pathway

S Yilmaz, Z Doğanyiğit, AO Oflamaz… - Chemical biology & …, 2023 - Wiley Online Library
In this study, the protective effect of melatonin was investigated in lipopolysaccharide
induced sepsis model. Twenty‐eight rats were randomly divided: Control, Melatonin, LPS …

Effects of short‐and long‐term use of propolis extracts on liver and kidney in rats

S Silici, S Demiray, A Okan, S Ertuğrul… - Food Science & …, 2024 - Wiley Online Library
Propolis is widely used as a supplementary food product for its health benefits. The aim of
this study was to determine the effects of commercial propolis extracts on the liver and …