GLP-1 programs the neurovascular landscape

B Chen, X Yu, C Horvath-Diano, MJ Ortuño… - Cell Metabolism, 2024 - cell.com
Readily available nutrient-rich foods exploit our inherent drive to overconsume, creating an
environment of overnutrition. This transformative setting has led to persistent health issues …

Metabolic Dysfunction in New‐Onset Idiopathic Intracranial Hypertension: Identification of Novel Biomarkers

JJ Korsbæk, RH Jensen, D Beier, EA Wibroe… - Annals of …, 2024 - Wiley Online Library
Objective Idiopathic intracranial hypertension (IIH) is a neurometabolic disease with an
increasing incidence. The pathophysiology is unknown, but improvement of diagnosis and …

Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

JH Wardman, MN Jensen, SN Andreassen… - Fluids and Barriers of …, 2023 - Springer
Background Idiopathic intracranial hypertension (IIH) is a condition characterized by
increased intracranial pressure (ICP), impaired vision, and headache. Most cases of IIH …

Effects of caffeine on intracranial pressure and pain perception in freely moving rats

IME Israelsen, CSJ Westgate… - … : The Journal of …, 2023 - Wiley Online Library
Objective Caffeine, a non‐selective adenosine receptor (AR) antagonist, is the most
consumed psychostimulant in the world. Caffeine has been suggested to regulate …

Obesity, body fat distribution and eye diseases

F Bosello, A Vanzo, C Zaffalon, L Polinelli… - Eating and Weight …, 2024 - Springer
Background The prevalence of obesity, a chronic disease, is increasing, and obesity is now
considered a global epidemic. Eye diseases are also increasing worldwide and have …

Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

CSJ Westgate, C Kamp‐Jensen… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Diseases of raised intracranial pressure (ICP) cause
severe morbidity and mortality. Multiple drugs are utilised to lower ICP including …

Personalized optimal nutrition lifestyle for self obesity management using metaalgorithms

S Chen, Y Dai, X Ma, H Peng, D Wang, Y Wang - Scientific Reports, 2022 - nature.com
Precision medicine applies machine learning methods to estimate the personalized optimal
treatment decision based on individual information, such as genetic data and medical …

A year in review: brain barriers and brain fluids research in 2022

RF Keep, HC Jones, MG Hamilton… - Fluids and Barriers of the …, 2023 - Springer
This aim of this editorial is to highlight progress made in brain barrier and brain fluid
research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers …

CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension

JH Wardman, SN Andreassen… - Fluids and Barriers of …, 2024 - Springer
Background Idiopathic intracranial hypertension (IIH) is a syndrome exhibiting elevated
intracranial pressure (ICP), visual disturbances, and severe headache. IIH primarily affects …

The impact of the migraine treatment onabotulinumtoxinA on inflammatory and pain responses: Insights from an animal model

PV Reducha, JP Bömers, L Edvinsson… - … : The Journal of Head …, 2024 - Wiley Online Library
Objective Migraine, a prevalent and debilitating disease, involves complex pathophysiology
possibly including inflammation and heightened pain sensitivity. The current study utilized …