Alzheimer's disease: epidemiology and clinical progression
AA Tahami Monfared, MJ Byrnes, LA White… - Neurology and …, 2022 - Springer
Alzheimer's disease (AD) is prevalent throughout the world and is the leading cause of
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …
A guide to conducting a meta-analysis with non-independent effect sizes
MWL Cheung - Neuropsychology review, 2019 - Springer
Conventional meta-analytic procedures assume that effect sizes are independent. When
effect sizes are not independent, conclusions based on these conventional procedures can …
effect sizes are not independent, conclusions based on these conventional procedures can …
Dementia in Down syndrome: unique insights for Alzheimer disease research
IT Lott, E Head - Nature Reviews Neurology, 2019 - nature.com
Virtually all adults with Down syndrome (DS) show the neuropathological changes of
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
[HTML][HTML] Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease
Abnormally phosphorylated tau, an indicator of Alzheimer's disease, accumulates in the first
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …
Rostral locus coeruleus integrity is associated with better memory performance in older adults
For decades, research into memory decline in human cognitive ageing has focused on
neocortical regions, the hippocampus and dopaminergic neuromodulation. Recent findings …
neocortical regions, the hippocampus and dopaminergic neuromodulation. Recent findings …
Speech-and language-based classification of Alzheimer's disease: a systematic review
Background: Alzheimer's disease (AD) has paramount importance due to its rising
prevalence, the impact on the patient and society, and the related healthcare costs …
prevalence, the impact on the patient and society, and the related healthcare costs …
When does cognitive decline begin? A systematic review of change point studies on accelerated decline in cognitive and neurological outcomes preceding mild …
Older adults who ultimately develop dementia experience accelerated cognitive decline
long before diagnosis. A similar acceleration in cognitive decline occurs in the years before …
long before diagnosis. A similar acceleration in cognitive decline occurs in the years before …
Optimizing detection of Alzheimer's disease in mild cognitive impairment: a 4-year biomarker study of mild behavioral impairment in ADNI and MEMENTO
Background Disease-modifying drug use necessitates better Alzheimer disease (AD)
detection. Mild cognitive impairment (MCI) leverages cognitive decline to identify the risk …
detection. Mild cognitive impairment (MCI) leverages cognitive decline to identify the risk …
Hearing impairment and cognition in an aging world
With the increasing number of older adults around the world, the overall number of dementia
cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million …
cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million …
Early detection of cognitive disturbances in mild cognitive impairment: a systematic review of observational studies
Mild cognitive impairment (MCI) is an intermediate state between normal cognition and early
dementia and is not considered as a typical outcome of brain aging. It has been estimated …
dementia and is not considered as a typical outcome of brain aging. It has been estimated …