Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …

Arsenic is a notorious element with the potential to harm exposed individuals in ways that
include cancerous and non-cancerous health complications. Millions of people across the …

Background Arsenic is a naturally occurring element that poses a significant threat to human
health due to its widespread presence in the environment, affecting millions worldwide …

Inorganic arsenic is a well-established human carcinogen, able to induce genetic and
epigenetic alterations. More than 200 million people worldwide are exposed to arsenic …

The conceptus is most vulnerable to developmental perturbation during its early stages
when the events that create functional organ systems are being launched. As the placenta is …

A complex network composed of at least 1900 microRNA (miRNA) species orchestrates the
development and function of the human placenta. These molecules regulate genes and …

For more than two decades, the view of the roles of non-coding RNAs (ncRNAs) has been
radically changing. These RNA molecules that are transcribed from our genome do not have …

Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs,
and species, which has been broadly recognized since the human ENCODE project and …

Aim: To understand miRNA changes across gestation in healthy human placentae. This is
essential before miRNAs can be used as biomarkers or prognostic indicators during …

Epidemiologic studies have shown an association between an adverse intrauterine
environment (eg, exposure to malnutrition) and an increased risk of developing …