Advances and challenges in modeling cannabidiol pharmacokinetics and hepatotoxicity
JL Beers, Z Zhou, KD Jackson - Drug Metabolism and Disposition, 2024 - ASPET
Cannabidiol (CBD) is a pharmacologically active metabolite of cannabis that is US Food and
Drug Administration approved to treat seizures associated with Lennox-Gastaut syndrome …
Drug Administration approved to treat seizures associated with Lennox-Gastaut syndrome …
Evaluation of cytochrome P450‐mediated cannabinoid‐drug interactions in healthy adult participants
S Bansal, CA Zamarripa, TR Spindle… - Clinical …, 2023 - Wiley Online Library
Understanding cannabis‐drug interactions is critical given regulatory changes that have
increased access to and use of cannabis. Cannabidiol (CBD) and Δ‐9 …
increased access to and use of cannabis. Cannabidiol (CBD) and Δ‐9 …
Sources of pharmacokinetic and pharmacodynamic variability and clinical pharmacology studies of antiseizure medications in the pediatric population
PD Maglalang, J Wen, CP Hornik… - Clinical and …, 2024 - Wiley Online Library
Multiple treatment options exist for children with epilepsy, including surgery, dietary
therapies, neurostimulation, and antiseizure medications (ASMs). ASMs are the first line of …
therapies, neurostimulation, and antiseizure medications (ASMs). ASMs are the first line of …
[HTML][HTML] Does acute cannabidiol (CBD) use impair performance? A meta-analysis and comparison with placebo and delta-9-tetrahydrocannabinol (THC)
Cannabidiol (CBD) is widely used and believed to be non-intoxicating, lacking acute
performance effects (eg, non-impairing). However, a synthesis of data has not evaluated …
performance effects (eg, non-impairing). However, a synthesis of data has not evaluated …
[HTML][HTML] CBD and THC in Special Populations: Pharmacokinetics and Drug–Drug Interactions
L Qian, JL Beers, KD Jackson, Z Zhou - Pharmaceutics, 2024 - mdpi.com
Cannabinoid use has surged in the past decade, with a growing interest in expanding
cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) applications into special …
cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) applications into special …
Cannabidiol Exposure Through Maternal Marijuana Use: Predictions in Breastfed Infants
Abstract Background and Objective Knowledge about exposure to cannabidiol (CBD) in
breastfed infants can provide an improved understanding of potential risk. The aim was to …
breastfed infants can provide an improved understanding of potential risk. The aim was to …
Quantification and Prediction of Human Fetal (-)-Δ9-tetrahydrocannabinol (THC)/11-OH-THC Exposure to Inform Neurodevelopmental Toxicity of Cannabis
AR Kumar - 2023 - search.proquest.com
Prenatal cannabis use is associated with various detrimental outcomes in the offspring, the
foremost being neurodevelopmental toxicity. Δ 9-tetrahydrocannabinol (THC) is the most …
foremost being neurodevelopmental toxicity. Δ 9-tetrahydrocannabinol (THC) is the most …