Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

Gut microbiota influence immunotherapy responses: mechanisms and therapeutic strategies

Y Lu, X Yuan, M Wang, Z He, H Li, J Wang… - Journal of hematology & …, 2022 - Springer
The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles

JT Morton, DM Jin, RH Mills, Y Shao, G Rahman… - Nature …, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …

A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The gut–brain axis

EA Mayer, K Nance, S Chen - Annual review of medicine, 2022 - annualreviews.org
Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

Gut microbiome lipid metabolism and its impact on host physiology

EM Brown, J Clardy, RJ Xavier - Cell Host & Microbe, 2023 - cell.com
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 …

Z Zhao, J Ning, X Bao, M Shang, J Ma, G Li, D Zhang - Microbiome, 2021 - Springer
Background Parkinson's disease (PD) is a prevalent neurodegenerative disorder, displaying
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …

[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions

L Chang, Y Wei, K Hashimoto - Brain Research Bulletin, 2022 - Elsevier
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

[HTML][HTML] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

Y Fan, RK Støving, S Berreira Ibraim… - Nature …, 2023 - nature.com
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are
women and it has a population prevalence of about 1%, but evidence-based treatment is …

[HTML][HTML] Role and mechanism of gut microbiota in human disease

Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …