The enteric nervous system (ENS) provides the intrinsic innervation of the bowel and is the
most neurochemically diverse branch of the peripheral nervous system, consisting of two …

The enteric nervous system (ENS) arises from neural crest-derived cells that migrate into
and along the gut, leading to the formation of a complex network of neurons and glial cells …

Correct development and maturation of the enteric nervous system (ENS) is critical for
survival. At birth, the ENS is immature and requires considerable refinement to exert its …

Secretory pathways within dendrites of neurons have been proposed for local transport of
newly synthesized proteins. However, little is known about the dynamics of the local …

Over the last 20 years, there has been increasing focus on the development of novel stem
cell based therapies for the treatment of disorders and diseases affecting the enteric nervous …

The enteric nervous system controls a variety of gastrointestinal functions including intestinal
motility. The minimal neuronal circuit necessary to direct peristalsis is well-characterized but …

The enteric nervous system (ENS) is sometimes called the “second brain” because of the
diversity of neuronal cell types and complex, integrated circuits that permit the ENS to …

Purinergic signalling plays major roles in the physiology and pathophysiology of digestive
organs. Adenosine 5′-triphosphate (ATP), together with nitric oxide and vasoactive …

During embryonic development, the gut is innervated by intrinsic (enteric) and extrinsic
nerves. Focusing on mammalian ENS development, in this Review we highlight how …

The nervous system of the bowel regulates the inflammatory phenotype of tissue resident
muscularis macrophages (MM), and in adult mice, enteric neurons are the main local source …