Microfluidic formulation of topological hydrogels for microtissue engineering
KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …
Brillouin microscopy: an emerging tool for mechanobiology
The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …
development and disease has widely been acknowledged, however standard techniques …
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Malignant transformation and tumour progression are associated with cancer-cell softening.
Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the …
Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the …
Physical phenotype of blood cells is altered in COVID-19
M Kubánková, B Hohberger, J Hoffmanns, J Fürst… - Biophysical journal, 2021 - cell.com
Clinical syndrome coronavirus disease 2019 (COVID-19) induced by severe acute
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …
Passive coupling of membrane tension and cell volume during active response of cells to osmosis
During osmotic changes of their environment, cells actively regulate their volume and
plasma membrane tension that can passively change through osmosis. How tension and …
plasma membrane tension that can passively change through osmosis. How tension and …
Label-free microfluidic cell sorting and detection for rapid blood analysis
N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
Mechanical adaptability of tumor cells in metastasis
The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will
successfully form life-threatening metastases when they undergo sequential steps along a …
successfully form life-threatening metastases when they undergo sequential steps along a …
A comparison of microfluidic methods for high-throughput cell deformability measurements
The mechanical phenotype of a cell is an inherent biophysical marker of its state and
function, with many applications in basic and applied biological research. Microfluidics …
function, with many applications in basic and applied biological research. Microfluidics …
Surface modification techniques for endothelial cell seeding in PDMS microfluidic devices
Microfluidic lab-on-a-chip cell culture techniques have been gaining popularity by offering
the possibility of reducing the amount of samples and reagents and greater control over …
the possibility of reducing the amount of samples and reagents and greater control over …
A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy
Cells can enter into a dormant state when faced with unfavorable conditions. However, how
cells enter into and recover from this state is still poorly understood. Here, we study …
cells enter into and recover from this state is still poorly understood. Here, we study …