Molecular testing for clinical diagnosis and epidemiological investigations of intestinal parasitic infections

JJ Verweij, CR Stensvold - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Over the past few decades, nucleic acid-based methods have been developed for the
diagnosis of intestinal parasitic infections. Advantages of nucleic acid-based methods are …

Schistosomiasis in areas of low endemicity: a new era in diagnosis

MG Cavalcanti, LF Silva, RHS Peralta, MGM Barreto… - Trends in …, 2013 - cell.com
Parasitological detection of Schistosoma is the cornerstone of schistosomiasis diagnosis in
areas of transmission worldwide. However, a steep decrease of sensitivity in low-endemicity …

Diagnosing polyparasitism in a high-prevalence setting in Beira, Mozambique: detection of intestinal parasites in fecal samples by microscopy and real-time PCR

L Meurs, AM Polderman… - PLoS neglected …, 2017 - journals.plos.org
Background Many different intestinal parasite species can co-occur in the same population.
However, classic diagnostic tools can only frame a particular group of intestinal parasite …

A Loop-Mediated Isothermal Amplification (LAMP) Assay for Early Detection of Schistosoma mansoni in Stool Samples: A Diagnostic Approach in a Murine Model

P Fernandez-Soto… - PLoS neglected …, 2014 - journals.plos.org
Background Human schistosomiasis, mainly due to Schistosoma mansoni species, is one of
the most prevalent parasitic diseases worldwide. To overcome the drawbacks of classical …

Is PCR the Next Reference Standard for the Diagnosis of Schistosoma in Stool? A Comparison with Microscopy in Senegal and Kenya

L Meurs, E Brienen, M Mbow, EA Ochola… - PLoS Neglected …, 2015 - journals.plos.org
Background The current reference test for the detection of S. mansoni in endemic areas is
stool microscopy based on one or more Kato-Katz stool smears. However, stool microscopy …

Factors impacting on progress towards elimination of transmission of schistosomiasis japonica in China

YB Zhou, S Liang, QW Jiang - Parasites & vectors, 2012 - Springer
Over the past decades China has made a great stride in controlling schistosomiasis,
eliminating transmission of Schistosoma japonicum in 5 provinces and remarkably reducing …

Development and Evaluation of a Sensitive PCR-ELISA System for Detection of Schistosoma Infection in Feces

LI Gomes, LHS Marques, MJ Enk… - PLoS Neglected …, 2010 - journals.plos.org
Background A PCR-enzyme-linked immunosorbent assay (PCR-ELISA) was developed to
overcome the need for sensitive techniques for the efficient diagnosis of Schistosoma …

Comparison of sensitivity and specificity of three diagnostic tests to detect Schistosoma mansoni infections in school children in Mwanza region, Tanzania

A Fuss, HD Mazigo, D Tappe, C Kasang, A Mueller - PloS one, 2018 - journals.plos.org
Background Schistosomiasis remains one of the most prevalent parasitic infections in the
world and has significant economic and public health consequences, particularly in poor …

Analysis of parasite and other skewed counts

N Alexander - Tropical medicine & international health, 2012 - Wiley Online Library
Objective To review methods for the statistical analysis of parasite and other skewed count
data. Methods Statistical methods for skewed count data are described and compared, with …

DNA amplification approaches for the diagnosis of key parasitic helminth infections of humans

CA Gordon, DJ Gray, GN Gobert… - Molecular and cellular …, 2011 - Elsevier
Parasitic helminths of humans are a major public health threat, particularly in developing
countries. The rapid and reliable diagnosis of helminth infections is central to their control as …