Mechanisms of homeostatic plasticity in the excitatory synapse

D Fernandes, AL Carvalho - Journal of neurochemistry, 2016 - Wiley Online Library
Brain development, sensory information processing, and learning and memory processes
depend on Hebbian forms of synaptic plasticity, and on the remodeling and pruning of …

TNF-Mediated Homeostatic Synaptic Plasticity: From in vitro to in vivo Models

R Heir, D Stellwagen - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Since it was first described almost 30 years ago, homeostatic synaptic plasticity (HSP) has
been hypothesized to play a key role in maintaining neuronal circuit function in both …

Bacterial peptidoglycans from microbiota in neurodevelopment and behavior

A Gonzalez-Santana, RD Heijtz - Trends in molecular medicine, 2020 - cell.com
It is increasingly recognized that the gut microbiota profoundly influences many aspects of
host development and physiology, including the modulation of brain development and …

Bacterial peptidoglycan as a driver of chronic brain inflammation

JD Laman, A Bert, C Power, R Dziarski - Trends in molecular medicine, 2020 - cell.com
Peptidoglycan (PGN) is a cell wall component of both Gram-positive and Gram-negative
bacteria. Signature fragments of PGN are proinflammatory through engagement of pattern …

Retrograde semaphorin–plexin signalling drives homeostatic synaptic plasticity

BO Orr, RD Fetter, GW Davis - Nature, 2017 - nature.com
Homeostatic signalling systems ensure stable but flexible neural activity and animal
behaviour,,,. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic …

Homeostatic control of Drosophila neuromuscular junction function

CA Frank, TD James, M Müller - Synapse, 2020 - Wiley Online Library
The ability to adapt to changing internal and external conditions is a key feature of biological
systems. Homeostasis refers to a regulatory process that stabilizes dynamic systems to …

Sensing the world and its dangers: an evolutionary perspective in neuroimmunology

A Kraus, KM Buckley, I Salinas - Elife, 2021 - elifesciences.org
Detecting danger is key to the survival and success of all species. Animal nervous and
immune systems cooperate to optimize danger detection. Preceding studies have …

Pattern recognition receptors from lepidopteran insects and their biological functions

Z Lin, JL Wang, Y Cheng, JX Wang, Z Zou - Developmental & Comparative …, 2020 - Elsevier
Lepidopteran insects have potent innate immunity to fight against the invading pathogens.
As the initiation step, pattern recognition receptors (PRRs) recognize and bind microbial …

Immune receptor signaling and the mushroom body mediate post-ingestion pathogen avoidance

JM Kobler, FJR Jimenez, I Petcu, ICG Kadow - Current Biology, 2020 - cell.com
In spite of the positive effects of bacteria on health, certain species are harmful, and
therefore, animals must weigh nutritional benefits against negative post-ingestion …

Beyond immunity: The Imd pathway as a coordinator of host defense, organismal physiology and behavior

Z Zhai, X Huang, Y Yin - Developmental & Comparative Immunology, 2018 - Elsevier
The humoral arm of host defense in Drosophila relies on two evolutionarily conserved NFκB
signaling cascades, the Toll and the immune deficiency (Imd) pathways. The Imd signaling …