Morpholine is a versatile moiety, a privileged pharmacophore and an outstanding
heterocyclic motif with wide ranges of pharmacological activities due to different …

Microbes are unique creatures that adapt to varying lifestyles and environment resistance in
extreme or adverse conditions. The genetic architecture of microbe may bear a significant …

This article purposes to provide insights to piperazine based molecular designs that will
facilitate drug discovery program in future. In our pursuit to summarize the reservoir of …

The syntheses of almost all N-heterocycles have now been successfully performed under
microwave irradiation and have provided significant improvements in the reaction time and …

A new series of pyrimidine (8, 14, 18 and 23) embellished analogues of 1, 5-
benzodiazepines were synthesized by the one-pot domino approach using the catalyst …

Aiming to obtain an efficient anti-proliferative activity, structure-and ligand-based drug
design approaches were expanded and utilized to design and refine a small compound …

In the present study, we have developed an efficient and green method for the synthesis of
pyrano [2, 3-d] pyrimidine-2, 4, 7-triones employing β-cyclodextrin as a catalyst in aqueous …

New series of 6-phenyl-2, 4-disubstituted pyrimidine-5-carbonitriles namely, 2-substitued
thio-6-phenyl-3, 4-dihydro-4-oxopyrimidine-5-carbonitriles (5a–d, 6, 7a–d, 8), 2-(4 …

The synthesis of novel series of benzofuran derivatives, containing barbitone moiety, 5-[(2/4-
substitutedphenyl)(5-substituted-1-benzofuran-2-yl) methylidene] pyrimidin-2, 4, 6 (1 H, 3 H …

This research aimed at synthesizing new potential anticonvulsants in the series of 2-(4-
methyl-6-oxo-1, 6-dihydropyrimidin-2-yl) thio-acetamides. An initial intermediate 6-methyl-2 …