Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG)
progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward …

Neurons are one of the highly polarized cells in the body. One of the fundamental issues in
neuroscience is how neurons establish their polarity; therefore, this issue fascinates many …

Background Inhibition of p38 MAPK signalling leads to glioblastoma multiform (GBM)
tumourigenesis. Nevertheless, the molecular mechanism that induces p38 MAPK signalling …

The hallmarks of FOXG1 syndrome, which results from mutations in a single FOXG1 allele,
include cortical atrophy and corpus callosum agenesis. However, the etiology for these …

Subtelomeric 1q43q44 microdeletions cause a syndrome associating intellectual disability,
microcephaly, seizures and anomalies of the corpus callosum. Despite several previous …

Cell polarity refers to the asymmetric distribution of signaling molecules, cellular organelles,
and cytoskeleton in a cell. Neural progenitors and neurons are highly polarized cells in …

Hypoxia‐ischemia (HI) of the brain not only impairs neurodevelopment but also causes
pineal gland dysfunction, which leads to circadian rhythm disruption. However, the …

Transcriptional mechanisms mediated by the binding of transcription factors (TFs) to cis-
acting regulatory elements (CREs) in DNA play crucial roles in directing gene expression …

Identification of rare genetic variants in patients with intellectual disability (ID) has been
greatly accelerated by advances in next generation sequencing technologies. However, due …

Objectives Acute lymphoblastic leukemia (ALL) is one of the most common malignancies in
children. Our aim was to identify a novel miRNA that can predict prognosis of childhood ALL …