Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …

Eph receptors and their ephrin ligands are viewed as promising targets for cancer treatment;
however, targeting them is hindered by their context-dependent functionalities. To …

EphB3 is a major key player in a variety of cellular activities, including cell migration,
proliferation, and apoptosis. However, the exact role of EphB3 in cancer remains …

Piper betle L. is a popular medicinal plant in Asia, and extracts of the plant leaf are used for
several therapeutics. It is known for its rich source of phenolic compounds, including …

Tyrosine kinase receptors (TKR) coordinate a variety of pathological processes in head and
neck squamous cell carcinoma (HNSCC), and eventually play a role in patient outcomes. In …

Singleton or low-frequency driver mutations are challenging to identify. We present a
domain driver mutation estimator (DOME) to identify rare candidate driver mutations. DOME …

The aggressive nature of glioblastoma multiforme (GBM) may be attributed to the
dysregulation of pathways driving both proliferation and invasion. EphrinB2, a membrane …

Aim EphB3 and dysadherin are involved in tumorigenesis and progression of many
neoplasms. However, the roles of EphB3 and dysadherin in extrahepatic …

Millet is recognized as a valuable source of energy and protein, renowned for its exceptional
nutritional composition enriched composed of micronutrients and phytochemicals. The …