The study of the metastatic cascade has revealed the complexity of the process and the
multiple cellular states that disseminated cancer cells must go through. The tumor …

Myeloid-derived suppressor cells (MDSCs) are important components of the tumor
microenvironment (TME), which drive the tumor immune escape by inducing …

Dormant, disseminated breast cancer cells resist treatment and may relapse into malignant
metastases after decades of quiescence. Identifying how and why these dormant breast …

Hypoxia, a common occurrence within solid tumors, can stimulate the dissemination of
deceptive tumor exosomes, which function as communicative bridges and orchestrate the …

Simple Summary Tumor dormancy continues to be a research hotspot with numerous
pressing problems that need to be solved. The goal of this study is to perform a bibliometric …

A significant proportion of patients treated for early breast cancer develop medium-term and
late distant recurrence. The delayed manifestation of metastatic disease is defined as …

If diagnosed prior to spread, surgical removal of cancer is curative. If metastases already
exist at the time of diagnosis, prognosis drops dramatically, and quality-of-life is significantly …

Autophagy is a conserved cellular process, and its dysfunction is implicated in cancer and
other diseases. Here, we employ an in vivo CRISPR screen targeting genes implicated in …

Clinical practice and clinical research heavily rely on primary tumors, circulating tumor DNA,
and/or overt metastases as sources of material for predicting or investigating breast cancer …

Breast cancer remains one of the leading causes of death in women around the world. A
majority of deaths from breast cancer occur due to cancer cells colonizing distant organ …