Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

B cell lymphomas are cancers that arise from cells that depend on numerous highly
orchestrated interactions with immune and stromal cells in the course of normal …

Purpose Although the life expectancy of patients with follicular lymphoma (FL) has
increased, little is known of their causes of death (CODs) in the rituximab era. Patients and …

Since Notch phenotypes in Drosophila melanogaster were first identified 100 years ago,
Notch signaling has been extensively characterized as a regulator of cell-fate decisions in a …

The hallmark t (14; 18)(q32; q21) in follicular lymphoma (FL) results in constitutive
overexpression of the BCL2 protein, allowing B cells to abrogate the default germinal center …

Most adult B cell lymphomas originate from germinal center (GC) B cells, but it is unclear to
what extent B cells in overt lymphoma retain the functional dynamics of GC B cells or are …

Practical and clinically focused, Abeloff's Clinical Oncology is a trusted medical reference
book designed to capture the latest scientific discoveries and their implications for cancer …

Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still
considered to be incurable. In recent years, whole-exome sequencing studies of large …

Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma in the
Western world. FL cell-intrinsic and cell-extrinsic factors influence FL biology and clinical …

Purpose The (14; 18) translocation constitutes both a genetic hallmark and critical early
event in the natural history of follicular lymphoma (FL). However, t (14; 18) is also detectable …