The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …

Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …

IgA nephropathy (IgAN) is the most common form of glomerulonephritis in pediatric
population. The clinical presentation of the disease in children ranges from microscopic …

Glucocorticoid receptor (GC), a founding member of the nuclear hormone receptor
superfamily, is a glucocorticoid-activated transcription factor that regulates gene expression …

While the incidence of nephrotic syndrome (NS) is decreasing in Korea, the morbidity of
difficult-to-treat NS is significant. Efforts to minimize treatment toxicity showed that prolonged …

Aim To investigate the need, in the Northern European setting, to perform kidney biopsy in
children with steroid‐sensitive nephrotic syndrome. Methods In this retrospective study 124 …

Dysregulation of the immune system can cause various glomerular diseases.
Immunosuppressive drugs may be required to manage or retard their progression. Though a …

A Japanese boy developed nephrotic syndrome (NS) and had microscopic hematuria at 8
years old. Renal biopsy was performed. Light microscopy study revealed mesangial …

Background Idiopathic steroid-resistant nephrotic syndrome (iSRNS) is a common problem
in pediatric nephrology. About 10%–20% of children with nephrotic syndrome have iSRNS …

Nephrotic syndrome is characterized by massive proteinuria, consequent hypoalbuminemia,
and edema. Frequently it is triggered by infection and asthma. The annual incidence of …