Single‐cell technologies have revolutionized research in the last decade, including for skin
biology. Single‐cell RNA sequencing has emerged as a powerful tool allowing the …

Chronic diabetic foot ulcers (DFUs) are a significant complication of diabetes mellitus, often
leading to amputation, increased morbidity, and a substantial financial burden. Even with the …

Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory skin disorder with a
prevalence of around 1% and a profound impact on patients' quality of life. Characteristic …

Background On the basis of the mounting evidence that type 17 T (T17) cells and increased
IL-17 play a key role in driving hidradenitis suppurativa (HS) lesion development, biologic …

Fibroblasts are critical pro-inflammatory regulators in chronic inflammatory and fibrotic skin
diseases. However, fibroblast heterogeneity and the absence of a unified cross-disease …

Hidradenitis Suppurativa (HS) is a chronic multifactorial inflammatory skin disease with
incompletely understood mechanisms of disease pathology. HS is characterized by aberrant …

Metal regulatory transcription factor 1 (MTF1) has been reported to be correlated with
several human diseases, especially like cancers. Exploring the underlying mechanisms and …

Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the skin that is brought
about by autoinflammation and hyperkeratosis at the pilosebaceous unit. The clinical …

Hidradenitis suppurativa (HS) is a chronic, debilitating inflammatory skin disease with a
poorly understood immunopathogenesis. Here, we report that HS lesional skin is …

Introduction Severe respiratory illness is the most prominent manifestation of patients
infected with SARS-CoV-2, and yet the molecular mechanisms underlying severe lung …