Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Epigenetic mechanisms in Alzheimer's disease

D Mastroeni, A Grover, E Delvaux, C Whiteside… - Neurobiology of …, 2011 - Elsevier
Epigenetic modifications help orchestrate sweeping developmental, aging, and disease-
causing changes in phenotype by altering transcriptional activity in multiple genes spanning …

Epigenetic and immune function profiles associated with posttraumatic stress disorder

M Uddin, AE Aiello, DE Wildman… - Proceedings of the …, 2010 - National Acad Sciences
The biologic underpinnings of posttraumatic stress disorder (PTSD) have not been fully
elucidated. Previous work suggests that alterations in the immune system are characteristic …

Environmental epigenetics of asthma: an update

SM Ho - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
Asthma, a chronic inflammatory disorder of the airway, is influenced by interplay between
genetic and environmental factors now known to be mediated by epigenetics. Aberrant DNA …

Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution

HK Somineni, X Zhang, JMB Myers, MB Kovacic… - Journal of Allergy and …, 2016 - Elsevier
Background Asthma is a complex disorder influenced by genetics and the environment.
Recent findings have linked abnormal DNA methylation in T cells with asthma; however, the …

Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow's milk allergy

R Berni Canani, L Paparo, R Nocerino, L Cosenza… - Clinical …, 2015 - Springer
Background Epigenetic changes in DNA methylation could regulate the expression of
several allergy-related genes. We investigated whether tolerance acquisition in children with …

Demethylation of the FCER1G promoter leads to FcεRI overexpression on monocytes of patients with atopic dermatitis

Y Liang, P Wang, M Zhao, G Liang, H Yin, G Zhang… - Allergy, 2012 - Wiley Online Library
To cite this article: Liang Y, Wang P, Zhao M, Liang G, Yin H, Zhang G, Wen H, Lu Q.
Demethylation of the FCER1G promoter leads to FcεRI overexpression on monocytes of …

Air pollution, epigenetics, and asthma

H Ji, JM Biagini Myers, EB Brandt, C Brokamp… - Allergy, Asthma & …, 2016 - Springer
Exposure to traffic-related air pollution (TRAP) has been implicated in asthma development,
persistence, and exacerbation. This exposure is highly significant as large segments of the …

Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice

M Mei, H Song, L Chen, B Hu, R Bai, D Xu… - Particle and Fibre …, 2018 - Springer
Background Epidemiological studies have suggested that elevated levels of air pollution
contribute to an increased incidence or severity of asthma. Although late-onset adult asthma …

Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention

S Manti, F Galletta, CL Bencivenga, I Bettini, A Klain… - Nutrients, 2024 - mdpi.com
Food allergy represents a global health problem impacting patients' and caregivers' quality
of life and contributing to increased healthcare costs. Efforts to identify preventive measures …