Dynamics of the preterm gut microbiome in health and disease

A Cuna, MJ Morowitz, I Ahmed… - American Journal of …, 2021 - journals.physiology.org
Advances in metagenomics have allowed a detailed study of the gut microbiome, and its
role in human health and disease. Infants born prematurely possess a fragile gut microbial …

The preterm gut microbiota: an inconspicuous challenge in nutritional neonatal care

JGE Henderickx, RD Zwittink… - Frontiers in cellular …, 2019 - frontiersin.org
The nutritional requirements of preterm infants are unique and challenging to meet in
neonatal care, yet crucial for their growth, development and health. Normally, the gut …

Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants

J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …

Probiotics: reiterating what they are and what they are not

G Reid, AA Gadir, R Dhir - Frontiers in microbiology, 2019 - frontiersin.org
It has been over seventeen years since the scientific definition of probiotics was crafted,
along with guidelines ensuring the appropriate use of the term. This definition is now used …

Candida–bacterial cross-kingdom interactions

KR Eichelberger, S Paul, BM Peters, JE Cassat - Trends in Microbiology, 2023 - cell.com
While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …

Necrotizing enterocolitis: the role of hypoxia, gut microbiome, and microbial metabolites

A Kaplina, S Kononova, E Zaikova, T Pervunina… - International Journal of …, 2023 - mdpi.com
Necrotizing enterocolitis (NEC) is a life-threatening disease that predominantly affects very
low birth weight preterm infants. Development of NEC in preterm infants is accompanied by …

Unraveling the microbiome of necrotizing enterocolitis: insights in novel microbial and metabolomic biomarkers

C Tarracchini, C Milani, G Longhi, F Fontana… - Microbiology …, 2021 - Am Soc Microbiol
Necrotizing enterocolitis (NEC) is among the most relevant gastrointestinal diseases
affecting mostly prematurely born infants with low birth weight. While intestinal dysbiosis has …

Gut and lung microbiota in preterm infants: immunological modulation and implication in neonatal outcomes

C Tirone, L Pezza, A Paladini, M Tana… - Frontiers in …, 2019 - frontiersin.org
In recent years, an aberrant gastrointestinal colonization has been found to be associated
with an higher risk for postnatal sepsis, necrotizing enterocolitis (NEC) and growth …

A systematic review of the factors influencing microbial colonization of the preterm infant gut

M Aguilar-Lopez, AM Dinsmoor, TTB Ho… - Gut …, 2021 - Taylor & Francis
Prematurity coupled with the necessary clinical management of preterm (PT) infants
introduces multiple factors that can interfere with microbial colonization. This study aimed to …

Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants

MR Asbury, S Shama, JY Sa, N Bando, J Butcher… - Cell Host & Microbe, 2022 - cell.com
Nutrient fortifiers are added to human milk to support the development of very-low-birth-
weight infants. Currently, bovine-milk-based fortifiers (BMBFs) are predominantly …