Oxidative stress and low-grade inflammation in polycystic ovary syndrome: controversies and new insights

A Mancini, C Bruno, E Vergani, C d'Abate… - International Journal of …, 2021 - mdpi.com
The pathophysiology of Polycystic Ovary Syndrome (PCOS) is quite complex and different
mechanisms could contribute to hyperandrogenism and anovulation, which are the main …

Myokines and heart failure: challenging role in adverse cardiac remodeling, myopathy, and clinical outcomes

AE Berezin, AA Berezin, M Lichtenauer - Disease Markers, 2021 - Wiley Online Library
Heart failure (HF) is a global medical problem that characterizes poor prognosis and high
economic burden for the health system and family of the HF patients. Although modern …

[HTML][HTML] Targeting FGF21 in cardiovascular and metabolic diseases: from mechanism to medicine

H Tan, T Yue, Z Chen, W Wu, S Xu… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Cardiovascular and metabolic disease (CVMD) is becoming increasingly prevalent in
developed and developing countries with high morbidity and mortality. In recent years …

When IGF-1 Meets Metabolic Inflammation and Polycystic Ovary Syndrome

X Li, S Lin, X Yang, C Chen, S Cao, Q Zhang… - International …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin
resistance (IR) and hyperandrogenaemia (HA). Metabolic inflammation (MI), characterized …

Cardioprotection and thyroid hormones in the clinical setting of heart failure

F Mastorci, L Sabatino, C Vassalle… - Frontiers in …, 2020 - frontiersin.org
Ischemic heart disease is the main cause of morbidity and mortality worldwide and is
becoming more widespread with population aging. Cardioprotection is a dynamic process …

Anabolic hormones deficiencies in heart failure with preserved ejection fraction: prevalence and impact on antioxidants levels and myocardial dysfunction

C Bruno, A Silvestrini, R Calarco… - Frontiers in …, 2020 - frontiersin.org
Purpose: In heart failure with reduced ejection fraction, catabolic mechanisms have a strong
negative impact on mortality and morbidity. The relationship between anabolic hormonal …

Tentative exploration of pharmacodynamic substances: Pharmacological effects, chemical compositions, and multi-components pharmacokinetic characteristics of …

L Hong, Y Zhao, W Chen, C Yang, G Li… - Frontiers in …, 2022 - frontiersin.org
The chemical components of Xin'an famous prescription Ershen Zhenwu Decoction
(ESZWD) are still unclear. The results showed that ESZWD could significantly reduce left …

Non-Thyroidal Illness in Chronic Renal Failure: Triiodothyronine Levels and Modulation of Extra-Cellular Superoxide Dismutase (ec-SOD)

A Mancini, A Silvestrini, F Marcheggiani, E Capobianco… - Antioxidants, 2024 - mdpi.com
Oxidative stress (OS) is implicated in several chronic diseases. Extra-cellular superoxide
dismutase (ec-SOD) catalyses the dismutation of superoxide anions with a protective role in …

[HTML][HTML] Metabolic remodeling induced by mitokines in heart failure

J Duan, Z Chen, Y Wu, B Zhu, L Yang, C Yang - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
The prevalence rates of heart failure (HF) are greater than 10% in individuals aged> 75
years, indicating an intrinsic link between aging and HF. It has been recognized that …

Application of blood pre-albumin and NT-pro BNP levels in evaluating prognosis of elderly chronic heart failure patients

L Shi, Y Zhang, J Zhang, Y Gao… - Experimental and …, 2020 - spandidos-publications.com
Levels of blood pre-albumin (PA) and N-terminal pro-B-type natriuretic peptide (NT-pro
BNP) in elderly patients with chronic heart failure (CHF) and their clinical value in prognosis …