Reduction of substrates by nitrogenases
Nitrogenase is the enzyme that catalyzes biological N2 reduction to NH3. This enzyme
achieves an impressive rate enhancement over the uncatalyzed reaction. Given the high …
achieves an impressive rate enhancement over the uncatalyzed reaction. Given the high …
Electron transfer in nitrogenase
HL Rutledge, FA Tezcan - Chemical reviews, 2020 - ACS Publications
Nitrogenase is the only enzyme capable of reducing N2 to NH3. This challenging reaction
requires the coordinated transfer of multiple electrons from the reductase, Fe-protein, to the …
requires the coordinated transfer of multiple electrons from the reductase, Fe-protein, to the …
Quantum mechanical calculations of redox potentials of the metal clusters in nitrogenase
We have calculated redox potentials of the two metal clusters in Mo-nitrogenase with
quantum mechanical (QM) calculations. We employ an approach calibrated for iron–sulfur …
quantum mechanical (QM) calculations. We employ an approach calibrated for iron–sulfur …
Geometry and electronic structure of the P-cluster in nitrogenase studied by combined quantum mechanical and molecular mechanical calculations and quantum …
We have studied the geometry and electronic structure of the P-cluster in nitrogenase in four
oxidation states: PN, P1+, P2+, and P3+. We have employed combined quantum …
oxidation states: PN, P1+, P2+, and P3+. We have employed combined quantum …
CowN sustains nitrogenase turnover in the presence of the inhibitor carbon monoxide
MS Medina, KO Bretzing, RA Aviles, KM Chong… - Journal of Biological …, 2021 - ASBMB
Nitrogenase is the only enzyme capable of catalyzing nitrogen fixation, the reduction of
dinitrogen gas (N 2) to ammonia (NH 3). Nitrogenase is tightly inhibited by the …
dinitrogen gas (N 2) to ammonia (NH 3). Nitrogenase is tightly inhibited by the …
Mutational analysis of the nitrogenase carbon monoxide protective protein CowN reveals that a conserved C-terminal glutamic acid residue is necessary for its activity
DL Willard, JJ Arellano, M Underdahl, TM Lee… - Biochemistry, 2023 - ACS Publications
Nitrogenase is the only enzyme that catalyzes the reduction of nitrogen gas into ammonia.
Nitrogenase is tightly inhibited by the environmental gas carbon monoxide (CO). Many …
Nitrogenase is tightly inhibited by the environmental gas carbon monoxide (CO). Many …
Investigating protein–Nanocrystal interactions for photodriven activity
AW Harris, A Harguindey, RE Patalano… - ACS Applied Bio …, 2020 - ACS Publications
We illustrate how intermolecular interactions facilitate ATP-free electron transfer between
either native or engineered MoFe protein (MoFeP) from nitrogenase and a CdS nanorod …
either native or engineered MoFe protein (MoFeP) from nitrogenase and a CdS nanorod …
Conformationally gated electron transfer in nitrogenase. Isolation, purification, and characterization of nitrogenase from Gluconacetobacter diazotrophicus
Nitrogenase is a complex, bacterial enzyme that catalyzes the ATP-dependent reduction of
dinitrogen (N 2) to ammonia (NH 3). In its most prevalent form, it consists of two proteins, the …
dinitrogen (N 2) to ammonia (NH 3). In its most prevalent form, it consists of two proteins, the …
De novo design of iron–sulfur proteins
Iron–sulfur proteins are one of the most abundant and functionally pliable redox proteins
found in all living organisms. Because of their crucial role in mediating electron transfer …
found in all living organisms. Because of their crucial role in mediating electron transfer …
Electron transfer proteins
Biological electron carriers are central to life. Numerous technological advances have
engendered rapid growth in the field between 2003 and 2018. Special emphasis is put on …
engendered rapid growth in the field between 2003 and 2018. Special emphasis is put on …