Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives

Y Yang, H Liu, Y Chen, N Xiao, Z Zheng, H Liu… - Cell Death & …, 2023 - nature.com
Non-small cell lung cancer (NSCLC) is one of the most threatening malignancies to human
health and life. In most cases, patients with NSCLC are already at an advanced stage when …

Extracellular vesicles in gastric cancer: role of exosomal lncRNA and microRNA as diagnostic and therapeutic targets

C Jiang, J Zhang, W Wang, Z Shan, F Sun… - Frontiers in …, 2023 - frontiersin.org
Extracellular vesicles (EVs), including exosomes, play a crucial role in intercellular
communication and have emerged as important mediators in the development and …

Different pathological response and histological features following neoadjuvant chemotherapy or chemo-immunotherapy in resected non-small cell lung cancer

G Alì, AM Poma, I Di Stefano, CC Zirafa… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-small cell lung cancer (NSCLC) is the leading cause of cancer incidence
and mortality worldwide. Neoadjuvant chemo-immunotherapy has led to clinical benefits in …

Pathology of Surgically Resected Lung Cancers Following Neoadjuvant Therapy

S Berezowska, M Keyter, H Bouchaab… - Advances in Anatomic …, 2024 - journals.lww.com
In around 30% of patients, non-small cell lung cancer is diagnosed at an advanced but
resectable stage. Adding systemic therapy has shown clear benefit over surgery alone in …

[HTML][HTML] Extracellular RNA profiles in non-small cell lung cancer plasma

Y Ni, W Zhang, G Mu, Y Gu, H Wang, K Wei… - Journal of Thoracic …, 2023 - ncbi.nlm.nih.gov
Background Non-small cell lung cancer (NSCLC) has a high mortality rate and poor
prognosis. The early detection of high-risk patients is essential to improve patient prognosis …

PD-L1 Expression and Tumour Microenvironment Patterns in Resected Non-Small-Cell Lung Cancer

G Gurevičienė, J Matulionė, L Poškienė, S Miliauskas… - Medicina, 2024 - mdpi.com
Background and Objectives: Although perioperative immunotherapy is implemented as a
standard of care for resected non-small cell lung cancer (NSCLC), there is unmet need for …

The Third Joint Meeting on Lung Cancer of the FHU OncoAge (University Côte d'Azur, Nice, France) and the University of Texas MD Anderson Cancer Center …

P Hofman, GA Calin, SA Mani, C Bontoux, M Ilié… - Cancers, 2022 - mdpi.com
We are proud and happy to present this Special Issue, a follow-up to the third joint meeting
on lung cancer of the FHU OncoAge (University Côte d'Azur, Nice, France) and the …

1207 Artificial intelligence-powered assessment of tumor microenvironment in pre-treatment and on-treatment biopsies informs treatment outcomes to pembrolizumab …

MH Derbala, KE McGonagle, H Batra, B Stephen… - 2024 - jitc.bmj.com
Background Pathologic tumor response and changes in the tumor microenvironment (TME)
following immunotherapy serve as surrogate markers to predict clinical outcomes in patients …

Immune microenvironment features underlying the superior efficacy of neoadjuvant immunochemotherapy over chemotherapy in local advanced gastric cancer Author

N Zhang, C Li, Z Zhao, W Wang, B Jiang, F Sun… - Frontiers in … - frontiersin.org
The therapeutic efficacy of neoadjuvant immunotherapy combined with chemotherapy (Io+
Chemo) is superior than chemotherapy alone (Chemo). However, the mechanism of Io+ …