Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in
SMN1 (encoding survival motor neuron protein (SMN)). Reduced expression of SMN leads …

DEAD-box decapping enzyme 20 (DDX20) is a putative RNA-decapping enzyme that can
be identified by the conserved motif Asp–Glu–Ala–Asp (DEAD). Cellular processes involve …

In the cell, RNA exists and functions in a complex with RNA binding proteins (RBPs) that
regulate each step of the RNA life cycle from transcription to degradation. Central to this …

Global statistics indicate that hepatocellular carcinoma (HCC) is the sixth most common
cancer and the third leading cause of cancer-related death. Protein phosphatase …

Spinal muscular atrophy (SMA) is caused by low levels of the survival of motoneuron (SMN)
Protein leading to preferential degeneration of lower motoneurons in the ventral horn of the …

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease
characterized by degeneration of lower motor neurons (LMNs), causing muscle weakness …

Cajal bodies (CBs) are subnuclear domains that contribute to the biogenesis of several
different classes of ribonucleoproteins (RNPs), including small nuclear RNPs. Only some …

Since its first identification as the gene responsible for spinal muscular atrophy (SMA), the
range of survival motor neuron (SMN) protein functions has increasingly expanded. This …

In selective autophagy, cargo recruitment is mediated by LC3-interacting regions (LIRs)/Atg8-
interacting motifs (AIMs) in the cargo or cargo receptor proteins. The binding of these motifs …

Alternative splicing (AS) is a common post-transcriptional regulatory process in eukaryotes.
AS has an irreplaceable role during plant development and in response to environmental …