Perivascular adipose tissue and coronary atherosclerosis: from biology to imaging phenotyping

A Lin, D Dey, DTL Wong, N Nerlekar - Current atherosclerosis reports, 2019 - Springer
Abstract Purpose of Review Perivascular adipose tissue (PVAT) has a complex, bidirectional
relationship with the vascular wall. In disease states, PVAT secretes pro-inflammatory …

Association of epicardial adipose tissue and high‐risk plaque characteristics: a systematic review and meta‐analysis

N Nerlekar, AJ Brown, RG Muthalaly… - Journal of the …, 2017 - Am Heart Assoc
Background Epicardial adipose tissue (EAT) is hypothesized to alter atherosclerotic plaque
composition, with potential development of high‐risk plaque (HRP). EAT can be measured …

Pericoronary adipose tissue computed tomography attenuation and high-risk plaque characteristics in acute coronary syndrome compared with stable coronary artery …

M Goeller, S Achenbach, S Cadet, AC Kwan… - JAMA …, 2018 - jamanetwork.com
Importance Pericoronary adipose tissue (PCAT) computed tomography (CT) attenuation
measured from coronary CT angiography (CTA) may be a promising metric in identifying …

Epicardial adipose tissue density and volume are related to subclinical atherosclerosis, inflammation and major adverse cardiac events in asymptomatic subjects

M Goeller, S Achenbach, M Marwan, MK Doris… - Journal of …, 2018 - Elsevier
Background We investigated whether epicardial adipose tissue (EAT) volume and density
are related to early atherosclerosis, plaque inflammation and major adverse cardiac events …

Pericoronary adipose tissue computed tomography attenuation distinguishes different stages of coronary artery disease: a cross-sectional study

A Lin, N Nerlekar, J Yuvaraj… - European Heart …, 2021 - academic.oup.com
Aims Vascular inflammation inhibits local adipogenesis in pericoronary adipose tissue
(PCAT) and this can be detected on coronary computed tomography angiography (CCTA) …

What is obesity?: Definition as a disease, with implications for care

JQ Purnell - Gastroenterology Clinics, 2023 - gastro.theclinics.com
Normal health, reproduction, and survival are dependent on the availability of lipids. Lipids
function as structural elements of cell membranes and lipoproteins,“sensing” molecules …

Metabolic syndrome, fatty liver, and artificial intelligence-based epicardial adipose tissue measures predict long-term risk of cardiac events: a prospective study

A Lin, ND Wong, A Razipour, PA McElhinney… - Cardiovascular …, 2021 - Springer
Background We sought to evaluate the association of metabolic syndrome (MetS) and
computed tomography (CT)-derived cardiometabolic biomarkers (non-alcoholic fatty liver …

Association of epicardial adipose tissue attenuation with coronary atherosclerosis in patients with a high risk of coronary artery disease

Z Liu, S Wang, Y Wang, N Zhou, J Shu, C Stamm… - Atherosclerosis, 2019 - Elsevier
Background and aims Density may indicate some tissue characteristics and help reveal the
role of epicardial adipose tissue (EAT) in coronary artery disease (CAD). Therefore, we …

Towards reference values of pericoronary adipose tissue attenuation: impact of coronary artery and tube voltage in coronary computed tomography angiography

R Ma, D Ties, M van Assen, GJ Pelgrim… - European …, 2020 - Springer
Objectives To determine normal pericoronary adipose tissue mean attenuation (PCAT MA)
values for left the anterior descending (LAD), left circumflex (LCX), and right coronary artery …

Epicardial adipose tissue: a novel potential imaging marker of comorbidities caused by chronic inflammation

MG Tarsitano, C Pandozzi, G Muscogiuri, S Sironi… - Nutrients, 2022 - mdpi.com
The observation of correlations between obesity and chronic metabolic and cardiovascular
diseases has led to the emergence of strong interests in “adipocyte biology”, in particular in …