Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …

Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

Synapses store information by long-lasting modifications of their structure and molecular
composition, but the precise chronology of these changes has not been studied at single …

Long-term potentiation (LTP) in the CA1 region of the hippocampus has been the primary
model by which to study the cellular and molecular basis of memory. Calcium/calmodulin …

While CaMKII has long been known to be essential for synaptic plasticity and learning,
recent work points to new dimensions of CaMKII function in the nervous system, revealing …

The synapse is a highly organized cellular specialization whose structure and composition
are reorganized, both positively and negatively, depending on the strength of input signals …

Calcium-and calmodulin-dependent protein kinase II (CaMKII) and glutamate receptors are
integrally involved in forms of synaptic plasticity that may underlie learning and memory. In …

▪ Abstract Highly enriched in brain tissue and present throughout the body, Ca2+/calmodulin-
dependent protein kinase II (CaMKII) is central to the coordination and execution of Ca2+ …

Ca2+/calmodulin (CaM)-dependent protein kinase (CaMKII) is a ubiquitous mediator of
Ca2+-linked signalling that phosphorylates a wide range of substrates to co-ordinate and …

Hyperpolarization-activated cation channels of the HCN gene family,,,,, contribute to
spontaneous rhythmic activity in both heart and brain,,. All four family members contain both …