Autophagy—a key player in cellular and body metabolism
KH Kim, MS Lee - Nature Reviews Endocrinology, 2014 - nature.com
Abstract Knowledge gained over the past 10 years about the mechanisms that underpin
autophagy has provided a universal framework for studies of diverse physiological and …
autophagy has provided a universal framework for studies of diverse physiological and …
Findings from the Quebec family study on the etiology of obesity: genetics and environmental highlights
Abstract The Quebec Family Study (QFS) was an observational study with three cycles of
data collection between 1979 and 2002 in Quebec City, Canada. The cohort is a mixture of …
data collection between 1979 and 2002 in Quebec City, Canada. The cohort is a mixture of …
Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice
M Rosell, M Kaforou, A Frontini… - American Journal …, 2014 - journals.physiology.org
Brown adipocytes dissipate energy, whereas white adipocytes are an energy storage site.
We explored the plasticity of different white adipose tissue depots in acquiring a brown …
We explored the plasticity of different white adipose tissue depots in acquiring a brown …
Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism
The molecular mechanism of autophagy and its relationship to other lysosomal degradation
pathways remain incompletely understood. Here, we identified a previously uncharacterized …
pathways remain incompletely understood. Here, we identified a previously uncharacterized …
Research status of the orphan G protein coupled receptor 158 and future perspectives
G-protein-coupled receptors (GPCRs) remain one of the most successful targets for
therapeutic drugs approved by the US Food and Drug Administration (FDA). Many novel …
therapeutic drugs approved by the US Food and Drug Administration (FDA). Many novel …
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American …
P Piaggi, I Masindova, YL Muller, J Mercader… - Diabetes, 2017 - Am Diabetes Assoc
Pima Indians living in Arizona have a high prevalence of obesity, and we have previously
shown that a relatively lower energy expenditure (EE) predicts weight and fat mass gain in …
shown that a relatively lower energy expenditure (EE) predicts weight and fat mass gain in …
Structure, Function, and Localization of Gβ5–RGS Complexes
VZ Slepak - Progress in molecular biology and translational …, 2009 - Elsevier
Members of the R7 subfamily of regulator of G protein signaling (RGS) proteins (RGS6, 7, 9,
and 11) exist as heterodimers with the G protein beta subunit Gβ5. These protein complexes …
and 11) exist as heterodimers with the G protein beta subunit Gβ5. These protein complexes …
Confounding by linkage disequilibrium
B Aissani - Journal of human genetics, 2014 - nature.com
Linkage disequilibrium (LD) and confounding are two widely discussed concepts in
Genetics and in Epidemiology, yet their relationship has received only intuitive or no …
Genetics and in Epidemiology, yet their relationship has received only intuitive or no …
[HTML][HTML] Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice
Q Wang, K Levay, T Chanturiya… - The FASEB …, 2011 - ncbi.nlm.nih.gov
We investigated the physiological role of Gβ5, a unique G protein β subunit that dimerizes
with regulators of G protein signaling (RGS) proteins of the R7 family instead of Gγ. Gβ5 is …
with regulators of G protein signaling (RGS) proteins of the R7 family instead of Gγ. Gβ5 is …
Family-based QTL mapping of heat stress tolerance in primitive tetraploid wheat (Triticum turgidum L.)
Identification of quantitative trait loci (QTL) and markers associated with heat and drought
tolerance is warranted for marker-assisted selection in wheat (Triticum aestivum L.) breeding …
tolerance is warranted for marker-assisted selection in wheat (Triticum aestivum L.) breeding …