Although awareness of familial hypercholesterolemia (FH) is increasing, this common,
potentially fatal, treatable condition remains underdiagnosed. Despite FH being a genetic …

Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Summary Background Homozygous familial hypercholesterolaemia (HoFH) is a rare
inherited disorder resulting in extremely elevated low-density lipoprotein cholesterol levels …

Familial hypercholesterolaemia is the most commonly encountered genetic condition that
predisposes individuals to premature cardiovascular disease. Nevertheless, most patients …

As atherosclerosis begins in childhood, early diagnosis and treatment of familial
hypercholesterolemia (FH) is considered necessary. The basic diagnosis of pediatric FH …

Familial hypercholesterolemia (FH) is an autosomal dominant condition that leads to
significantly elevated low-density lipoprotein cholesterol (LDL-C) levels and an elevated risk …

Familial hypercholesterolemia (FH) is one of the most common genetic disorders in humans.
It is an extremely atherogenic metabolic disorder characterized by lifelong elevations of …

Aims Lomitapide is a lipid-lowering agent indicated as an adjunct therapy for adult
homozygous familial hypercholesterolaemia (HoFH). This study evaluated the medium-term …

Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic
variants in FH‐causing genes as well as from a polygenic cause. We evaluated the …

Abstract Purpose of Review Homozygous familial hypercholesterolemia (HoFH) is a rare,
genetic condition characterized by high levels of Low density lipoprotein cholesterol (LDL …