Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic
homeostasis of this essential trace element. This review summarizes the key aspects of …

In nature, land plants as sessile organisms are faced with multiple nutrient stresses that
often occur simultaneously in soil. Nitrogen (N), phosphorus (P), sulfur (S), zinc (Zn), and …

The nutritional essentiality of zinc for the growth of living organisms had been recognized
long before zinc biochemistry began with the discovery of zinc in carbonic anhydrase in …

The use of the essential element zinc (Zn) in the biochemistry of land plants is widespread,
and thus comparable to that in other eukaryotes. Plants have evolved the ability to adjust to …

The human prostate gland contains extremely high zinc levels; which is due to the
specialized zinc-accumulating acinar epithelial of the peripheral zone. These cells evolved …

Our knowledge of the molecular mechanisms of intracellular homeostatic control of zinc ions
is now firmly grounded on experimental findings gleaned from the study of zinc proteomes …

We developed genetically encoded fluorescence resonance energy transfer (FRET)-based
sensors that display a large ratiometric change upon Zn2+ binding, have affinities that span …

Zn2+ plays essential roles in various physiological processes in living systems, and the
investigation of Zn2+ related physiology and pathology has attracted considerable interest …

The trace element zinc is essential for the immune system, and zinc deficiency affects
multiple aspects of innate and adaptive immunity. There are remarkable parallels in the …

The importance of Zn for human health becomes obvious during Zn deficiency. Even mild
insufficiencies of Zn cause alterations in haematopoiesis and immune functions, resulting in …