In vitro cytotoxicity assay, mushroom tyrosinase inhibitory activity and release analysis of kojic monooleate nanodelivery system and in silico molecular docking study …

MA Roselan, N Zakaria, NH Faujan, MAM Latif… - Journal of Drug Delivery …, 2021 - Elsevier
Tyrosinase is the main enzyme that catalyzes the browning of fruits, fungi and vegetables,
and melanogenesis process in mammals. Kojic monooleate (KMO) is an ester produced via …

Potential peptidyl arginine deiminase type 4 inhibitors from Morinda citrifolia: a structure-based drug design approach

D Roy Chowdhury, R Ghosh, S Debnath… - In Silico Pharmacology, 2023 - Springer
Abstract The World Health Organization estimates that more than 23 million individuals
worldwide suffer from rheumatoid arthritis (RA), a chronic systemic autoimmune disease and …

Impact of GSK199 and GSK106 binding on protein arginine deiminase IV stability and flexibility: A computational approach

HHZ Fithri, Z Ibrahim, EZ Ali - Computational Biology and Chemistry, 2023 - Elsevier
Protein arginine deiminase IV (PAD4) is a potential target for diseases including rheumatoid
arthritis and cancers. Currently, GSK199 is a potent, selective yet reversible PAD4 inhibitor …

Introductory chapter: The emerging corner of the omics studies for rational drug design

AA Parikesit - Drug Design-Novel Advances in the Omics Field …, 2021 - books.google.com
The Acceleration of COVID-19 research in Proteomics and Transcriptomics studies occurred
swiftly due to the massive amount of investment and advances in biomanufacturing [1, 2] …

[PDF][PDF] A preliminary study: molecular docking, optimization and characterization of kojic monooleate nanoemulsion for cosmeceuticals application

RM AZIMUDDIN, Z NORZALINA… - Journal of Sustainability …, 2021 - researchgate.net
Skin hyperpigmentation disease occurs when there is an abnormal production of melanin
synthesized in the melanocyte. One of the kojic acid derivatives, namely kojic monooleate …

Impact of GSK199 and GSK106 binding on protein arginine deiminase IV stability and flexibility:: A computational approach

HH Zainal Fithri, Z Ibrahim, EZ Ali - 2023 - dl.acm.org
Protein arginine deiminase IV (PAD4) is a potential target for diseases including rheumatoid
arthritis and cancers. Currently, GSK199 is a potent, selective yet reversible PAD4 inhibitor …