Emerging evidence suggests that partially distinct mechanisms may underlie the association
between different dimensions of early life adversity (ELA) and psychopathology in children …

Physical, sexual, and emotional abuse and various forms of neglect of children are
associated with substantially increased risk for concurrent and subsequent psychopathology …

Foster care is the preferred type of out-of-home placement for children and youth when they
are not able to live with their own parents. However, placement instability, and its effect on …

Hypotheses concerning the biologic embedding of early adversity via developmental
neuroplasticity mechanisms have been proposed on the basis of experimental studies in …

The human brain requires a wide variety of experiences and environmental inputs in order
to develop normally. Children who are neglected by caregivers or raised in institutional …

Experience plays an essential role in building brain architecture after birth. The question we
address in this paper is what happens to brain and behavior when a young child is deprived …

Exposure to adversity in childhood is associated with elevations in numerous physical and
mental health outcomes across the life course. The biological embedding of early …

The mechanisms by which childhood maltreatment increases anxiety is unclear, but a
propensity for increased defensive behavior in rodent models of early life stress (ELS) …

Executive functions (EFs) are cognitive processes that support flexible goal pursuit. Healthy
development of EFs during childhood is critical for later life outcomes including health …

Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …