The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as …

Tuberculosis (TB) has been responsible for the greatest number of human deaths due to an
infectious disease in general, and due to antimicrobial resistance (AMR) in particular. The …

Tuberculosis, disease caused by Mycobacterium tuberculosis, is currently the leading cause
of death by a single infectious agent worldwide. Early, rapid and accurate identification of M …

Background Multidrug resistant tuberculosis (MDR-TB) remains a serious public health
problem with poor treatment outcomes. Predictors of poor outcomes vary in different regions …

Currently, mutations in three genes, namely rrs, rpsL, and gidB, encoding 16S rRNA,
ribosomal protein S12, and 16S rRNA-specific methyltransferase, respectively, are …

Background: Tuberculosis, mainly caused by Mycobacterium tuberculosis (Mtb), is an
ancient human disease that gravely affects millions of people annually. We wanted to …

Mutations in rpsL, rrs, and gidB are well linked to streptomycin (STR) resistance, some of
which are suggested to be potentially associated with Mycobacterium tuberculosis genotypic …

Our objective was to evaluate the performance of whole-genome sequencing (WGS) from
early positive liquid cultures for predicting Mycobacterium tuberculosis complex (MTBC) …

Beijing genotype strains are divided into two major sublineages, ancient (atypical) and
modern (typical) types, but their phenotypic variations remain largely unknown …

The objectives of this study were to characterise mutations in rrs, rpsL and gidB genes in
Mycobacterium tuberculosis isolates from Thailand and to examine possible associations …