Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene
expression according to parental origin. It has long been established that imprinted genes …

Many lines of evidence, including epidemiologic data and extensive clinical and
experimental studies, indicate that early life events play a powerful role in influencing later …

Variations in phenotype reflect the influence of environmental conditions during
development on cellular functions, including that of the genome. The recent integration of …

ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

Much attention has been given to the idea of transgenerational epigenetic inheritance, but
fundamental questions remain regarding how much takes place and the impact that this …

There are numerous examples in psychology and other disciplines of the enduring effects of
early experience on neural function. In this article, we review the emerging evidence for …

Genomic imprinting causes genes to be expressed or repressed depending on their
parental origin. The majority of imprinted genes identified to date map in clusters and much …

Fundamental to genomic imprinting in mammals is the acquisition of epigenetic marks that
differ in male and female gametes at 'imprinting control regions'(ICRs). These marks mediate …

Background Changes in imprinted gene dosage in the placenta may compromise the
prenatal control of nutritional resources. Indeed monoallelic behaviour and sensitivity to …